I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Structural insights into cobalamin loading and reactivation of human methionine synthase
Human methionine synthase (MTR) is an essential enzyme of one carbon metabolism. Consisting of a catalytic N-half and a cobalamin binding C-half, MTR utilises this intricate organometallic cofactor in...
www.biorxiv.org
November 11, 2025 at 12:48 PM
I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Special Issue: Macromolecular Assemblies is now live! Explore advances in cryoEM, cryoET, FIB milling, NMR, & AI for structure prediction. Discover cutting-edge insights into the structure & function of biological complexes. #StructuralBiology #CryoEM
spkl.io/63324AwAho
spkl.io/63324AwAho
November 10, 2025 at 1:00 PM
Special Issue: Macromolecular Assemblies is now live! Explore advances in cryoEM, cryoET, FIB milling, NMR, & AI for structure prediction. Discover cutting-edge insights into the structure & function of biological complexes. #StructuralBiology #CryoEM
spkl.io/63324AwAho
spkl.io/63324AwAho
Grateful to have received the Wilhelm und Else Heraeus-Stiftung Research Fellowship, to support my group’s work at the Ernst Ruska-Centre (ER-C) of Forschungszentrum Jülich #cryoem
November 9, 2025 at 9:26 AM
Grateful to have received the Wilhelm und Else Heraeus-Stiftung Research Fellowship, to support my group’s work at the Ernst Ruska-Centre (ER-C) of Forschungszentrum Jülich #cryoem
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
November 5, 2025 at 12:12 PM
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
November 6, 2025 at 3:46 PM
Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
Seeing is believing-Plasmodium falciparum translation in action pubmed.ncbi.nlm.nih.gov/41202797/ #cryoem
November 8, 2025 at 9:58 PM
Seeing is believing-Plasmodium falciparum translation in action pubmed.ncbi.nlm.nih.gov/41202797/ #cryoem
Molecular architecture and diversity of StopGo/2A translational recoding www.biorxiv.org/content/10.1101/2025.11.07.687186v1 #cryoem
November 8, 2025 at 3:04 PM
Molecular architecture and diversity of StopGo/2A translational recoding www.biorxiv.org/content/10.1101/2025.11.07.687186v1 #cryoem
Topological defects drive influenza glycoprotein lattice assembly on spherical membranes www.biorxiv.org/content/10.1101/2025.11.06.686978v1 #cryoem
November 8, 2025 at 12:46 PM
Topological defects drive influenza glycoprotein lattice assembly on spherical membranes www.biorxiv.org/content/10.1101/2025.11.06.686978v1 #cryoem
Systematic membrane thickness variation across cellular organelles revealed by cryo-ET pubmed.ncbi.nlm.nih.gov/41186573/ #cryoem
November 5, 2025 at 9:58 PM
Systematic membrane thickness variation across cellular organelles revealed by cryo-ET pubmed.ncbi.nlm.nih.gov/41186573/ #cryoem
Cryo-electron microscopy visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2 pubmed.ncbi.nlm.nih.gov/41196948/ #cryoem
November 8, 2025 at 12:10 AM
Cryo-electron microscopy visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2 pubmed.ncbi.nlm.nih.gov/41196948/ #cryoem
Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! 🇳🇱🔬
Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠
www.uu.nl/en/news/33-m...
Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠
www.uu.nl/en/news/33-m...
33 million euro investment for national electron microscope facility EMPower
A major new national facility for electron microscopy, called EMPower, has been awarded to a consortium of Dutch universities and medical centers. EMPower aims to pave the way for major discoveries im...
www.uu.nl
November 3, 2025 at 4:47 PM
Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! 🇳🇱🔬
Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠
www.uu.nl/en/news/33-m...
Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠
www.uu.nl/en/news/33-m...
Here you can see a cryoEM structure of the Clostridium botulinum OLE non-coding RNA (PDB code: 9LCR)
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #ncRNA #clostridium #sensor #OLE #cryoem
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #ncRNA #clostridium #sensor #OLE #cryoem
November 10, 2025 at 11:00 AM
Here you can see a cryoEM structure of the Clostridium botulinum OLE non-coding RNA (PDB code: 9LCR)
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #ncRNA #clostridium #sensor #OLE #cryoem
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #ncRNA #clostridium #sensor #OLE #cryoem
Lessons learned from a Kaggle challenge for particle picking in cryo-electron tomography www.biorxiv.org/content/10.1101/2025.11.03.686153v1 #cryoem
November 6, 2025 at 12:21 PM
Lessons learned from a Kaggle challenge for particle picking in cryo-electron tomography www.biorxiv.org/content/10.1101/2025.11.03.686153v1 #cryoem
Stephen Muench provides an historical overview of #cryoEM from “blobology” to state-of-the-art atomic resolution today. #NorthernEye
November 5, 2025 at 10:36 AM
Stephen Muench provides an historical overview of #cryoEM from “blobology” to state-of-the-art atomic resolution today. #NorthernEye
The molecular basis of μ-opioid receptor signaling plasticity pubmed.ncbi.nlm.nih.gov/41199005/ #cryoem
November 7, 2025 at 10:10 AM
The molecular basis of μ-opioid receptor signaling plasticity pubmed.ncbi.nlm.nih.gov/41199005/ #cryoem
Neutralizing antibodies against Chikungunya virus and structural elucidation of their mechanism of action pubmed.ncbi.nlm.nih.gov/41184282/ #cryoem
November 4, 2025 at 10:15 AM
Neutralizing antibodies against Chikungunya virus and structural elucidation of their mechanism of action pubmed.ncbi.nlm.nih.gov/41184282/ #cryoem
We’re heading to #PSDI2025!
Meet the CryoCloud team and don’t miss our talks:
⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis
🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud
Drop by our booth or book a chat 👇
connect.cryocloud.io/meetings/cry...
#CryoEM #XrayCrystallography
Meet the CryoCloud team and don’t miss our talks:
⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis
🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud
Drop by our booth or book a chat 👇
connect.cryocloud.io/meetings/cry...
#CryoEM #XrayCrystallography
November 5, 2025 at 8:39 AM
We’re heading to #PSDI2025!
Meet the CryoCloud team and don’t miss our talks:
⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis
🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud
Drop by our booth or book a chat 👇
connect.cryocloud.io/meetings/cry...
#CryoEM #XrayCrystallography
Meet the CryoCloud team and don’t miss our talks:
⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis
🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud
Drop by our booth or book a chat 👇
connect.cryocloud.io/meetings/cry...
#CryoEM #XrayCrystallography
#BNMRZ Symposium 2025
Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies
💻 Online attendance is still possible: t1p.de/zdr8j
👉 Further information: t1p.de/rjuz4
@tum.de
#StructuralBiology #CryoEM #AI #TherapeuticInnovations
Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies
💻 Online attendance is still possible: t1p.de/zdr8j
👉 Further information: t1p.de/rjuz4
@tum.de
#StructuralBiology #CryoEM #AI #TherapeuticInnovations
November 6, 2025 at 9:19 AM
#BNMRZ Symposium 2025
Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies
💻 Online attendance is still possible: t1p.de/zdr8j
👉 Further information: t1p.de/rjuz4
@tum.de
#StructuralBiology #CryoEM #AI #TherapeuticInnovations
Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies
💻 Online attendance is still possible: t1p.de/zdr8j
👉 Further information: t1p.de/rjuz4
@tum.de
#StructuralBiology #CryoEM #AI #TherapeuticInnovations
Deciphering the molecular mechanism of the bacterial division motor TolQRA pubmed.ncbi.nlm.nih.gov/41184225/ #cryoem
November 4, 2025 at 12:21 PM
Deciphering the molecular mechanism of the bacterial division motor TolQRA pubmed.ncbi.nlm.nih.gov/41184225/ #cryoem
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor pubmed.ncbi.nlm.nih.gov/41168429/ #cryoem
November 2, 2025 at 12:46 AM
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor pubmed.ncbi.nlm.nih.gov/41168429/ #cryoem
Membrane and vesicle structure detection in cryo-electron tomography based on deep learning pubmed.ncbi.nlm.nih.gov/41176036/ #cryoem
November 2, 2025 at 12:46 PM
Membrane and vesicle structure detection in cryo-electron tomography based on deep learning pubmed.ncbi.nlm.nih.gov/41176036/ #cryoem
On a gruelling hunt for rare associated molecules in your #cryoEM particle stack and not sure where to look?
Discover practical tips and tricks in our new case study using #CryoSPARC v4.7.1 where we find and refine a low-population interaction partner!
guide.cryosparc.com/processing-d...
Discover practical tips and tricks in our new case study using #CryoSPARC v4.7.1 where we find and refine a low-population interaction partner!
guide.cryosparc.com/processing-d...
October 30, 2025 at 1:33 PM
On a gruelling hunt for rare associated molecules in your #cryoEM particle stack and not sure where to look?
Discover practical tips and tricks in our new case study using #CryoSPARC v4.7.1 where we find and refine a low-population interaction partner!
guide.cryosparc.com/processing-d...
Discover practical tips and tricks in our new case study using #CryoSPARC v4.7.1 where we find and refine a low-population interaction partner!
guide.cryosparc.com/processing-d...
SND3 is the membrane insertase within a distinct SEC61 translocon complex pubmed.ncbi.nlm.nih.gov/41162385/ #cryoem
November 1, 2025 at 12:25 AM
SND3 is the membrane insertase within a distinct SEC61 translocon complex pubmed.ncbi.nlm.nih.gov/41162385/ #cryoem