zhaolabucr.bsky.social
@zhaolabucr.bsky.social
Congratulations to the Zhao lab members and collaborators on demonstrating the formation and biological implications of a new type of mitochondrial DNA damage @pnas.org www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 25, 2025 at 5:34 PM
Congratulations to Dr. Anal Jana & Yu Hsuan Chen on publishing our work on a novel mitochondria-targeting probe for manipulating mitochondrial DNA @angewandtechemie.bsky.social Thanks to @ucriverside.bsky.social for providing funding for open access! onlinelibrary.wiley.com/doi/10.1002/...
Mitochondria‐Targeting Abasic Site‐Reactive Probe (mTAP) Enables the Manipulation of Mitochondrial DNA Levels
Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory responses. Defects in mtDNA are impl...
onlinelibrary.wiley.com
July 17, 2025 at 3:41 PM
Congrats to Dr. Anal Jana and Yu Hsuan Chen for developing and validating a mitochondria-targeting probe that can rescue mtDNA damage-induced mtDNA level decrease! chemrxiv.org/engage/chemr...
Mitochondria-targeting abasic site-reactive probe (mTAP) enables the manipulation of mitochondrial DNA repair and turnover
Mitochondrial DNA (mtDNA) encodes essential protein subunits in the oxidative phosphorylation system and a set of tRNAs and rRNAs, making it critical for mitochondrial and cellular functions. Defects ...
chemrxiv.org
April 9, 2025 at 8:35 PM
Happy to share our new story on the role of TFAM in regulating mitochondrial DNA repair and lesion accumulation. academic.oup.com/nar/advance-...
DNA sequence and lesion-dependent mitochondrial transcription factor A (TFAM)-DNA-binding modulates DNA repair activities and products
Abstract. Mitochondrial DNA (mtDNA) is indispensable for mitochondrial function and is maintained by DNA repair, turnover, mitochondrial dynamics and mitop
academic.oup.com
December 8, 2024 at 8:31 PM