Zac White
@zac-white.bsky.social
Ph.D | Sano lab
UIC Microbiology and Immunology
Mucosal Immunologist
Focused on the gut microbiome’s influence on innate and adaptive immune cells
UIC Microbiology and Immunology
Mucosal Immunologist
Focused on the gut microbiome’s influence on innate and adaptive immune cells
Im thrilled to share that our manuscript is online now at Nature.
www.nature.com/articles/s41...
In this study we find novel cross reactivity between commensal specific T cells and host proteins. This highlights mechanisms that influence commensal-induced autoimmunity.
www.nature.com/articles/s41...
In this study we find novel cross reactivity between commensal specific T cells and host proteins. This highlights mechanisms that influence commensal-induced autoimmunity.
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation - Nature
Dysregulated CD4 T cells that recognize gut commensal antigens are able to infiltrate the central nervous systems and are re-stimulated by host proteins, resulting in neuroinflammation.
www.nature.com
June 18, 2025 at 4:38 PM
Im thrilled to share that our manuscript is online now at Nature.
www.nature.com/articles/s41...
In this study we find novel cross reactivity between commensal specific T cells and host proteins. This highlights mechanisms that influence commensal-induced autoimmunity.
www.nature.com/articles/s41...
In this study we find novel cross reactivity between commensal specific T cells and host proteins. This highlights mechanisms that influence commensal-induced autoimmunity.
Excited to share our latest story is out now in Immunity. A great collaboration between the Sano and Kim labs at UIC.
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis: Immunity www.cell.com/immunity/ful...
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis: Immunity www.cell.com/immunity/ful...
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis
Immune-microbiota interactions are required to maintain host homeostasis. Kim et al.
identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents
spontaneous lung inflammat...
www.cell.com
April 29, 2025 at 3:30 PM
Excited to share our latest story is out now in Immunity. A great collaboration between the Sano and Kim labs at UIC.
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis: Immunity www.cell.com/immunity/ful...
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis: Immunity www.cell.com/immunity/ful...