Yupei You
youyupei.bsky.social
Yupei You
@youyupei.bsky.social
Postdoctoral researcher at the Walter and Eliza Hall Institute in Matt Ritchie’s lab.

Research topic: Genomics | Transcriptomics | Long-read sequencing | Single-cell sequencing.
🔹 Access & reuse
The entire dataset is openly available for anyone developing tools or benchmarking long-read technologies.
September 15, 2025 at 5:28 AM
🔹 What’s inside
• Bulk, single-cell & single-nucleus RNA-seq from 8 lung-cancer cell lines spanning 3 cancer types for realistic DE analysis
• Three long-read protocols (ONT PCR-cDNA, ONT direct RNA, PacBio Kinnex) and Illumina short-read sequencing
• Synthetic spike-in controls for ground truth
September 15, 2025 at 5:26 AM
🔹 Why it matters
LongBench enables rigorous cross-platform comparisons of gene & isoform quantification, differential expression, alternative splicing, and allele-specific expression—helping the community evaluate and improve long-read methods.
September 15, 2025 at 5:14 AM