@youngjunpark.bsky.social
Reposted
We show that the HKU25 clade of merbecoviruses utilizes the ACE2 receptor with a binding mode sharing similarity to HKU5, suggesting a common evolutionary origin of ACE2 utilization.
Led by Young-Jun Park on our side.
Collab with Huan Yan's lab!
@hhmi.bsky.social
www.biorxiv.org/content/10.1...
Led by Young-Jun Park on our side.
Collab with Huan Yan's lab!
@hhmi.bsky.social
www.biorxiv.org/content/10.1...
ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution
Dipeptidyl peptidase-4 (DPP4) is a well-established receptor for several MERS-related coronaviruses (MERSr-CoVs) isolated from humans, camels, pangolins, and bats. However, the receptor usage of many ...
www.biorxiv.org
February 21, 2025 at 2:12 AM
We show that the HKU25 clade of merbecoviruses utilizes the ACE2 receptor with a binding mode sharing similarity to HKU5, suggesting a common evolutionary origin of ACE2 utilization.
Led by Young-Jun Park on our side.
Collab with Huan Yan's lab!
@hhmi.bsky.social
www.biorxiv.org/content/10.1...
Led by Young-Jun Park on our side.
Collab with Huan Yan's lab!
@hhmi.bsky.social
www.biorxiv.org/content/10.1...