Daniel Ríos
@yosoyden.bsky.social
Drosophila scientist at UNAM in Mexico City
Interested in #devbio, #cellbio, #microscopy, #imageanalysis, #genderequality, #bouldering, and other things. Parent of two cats and one dog :)
Interested in #devbio, #cellbio, #microscopy, #imageanalysis, #genderequality, #bouldering, and other things. Parent of two cats and one dog :)
Finally, we did the opposite: We altered the rate of dorsal closure and looked at what happened to the trunks. Again, we found wavy tracheal trunks that followed the movements of the epidermis (9/13)
March 17, 2025 at 5:21 PM
Finally, we did the opposite: We altered the rate of dorsal closure and looked at what happened to the trunks. Again, we found wavy tracheal trunks that followed the movements of the epidermis (9/13)
We degraded beta-integrin in the tracheal system using nanobodies. Again, we saw the wavy phenotype in the trunks. To our surprise this also affected the speed of dorsal closure, suggesting that the adhesion of the trunks to the epidermis influences epidermal development (8/13)
March 17, 2025 at 5:21 PM
We degraded beta-integrin in the tracheal system using nanobodies. Again, we saw the wavy phenotype in the trunks. To our surprise this also affected the speed of dorsal closure, suggesting that the adhesion of the trunks to the epidermis influences epidermal development (8/13)
We visited @embl.org thanks to @eurobioimaging.bsky.social to cut these protrusions using lasers. We found they were under tension, which supported a they had a mechanical function (6/13)
March 17, 2025 at 5:21 PM
We visited @embl.org thanks to @eurobioimaging.bsky.social to cut these protrusions using lasers. We found they were under tension, which supported a they had a mechanical function (6/13)
If these protruding cells of the trunks adhered to tendon cells, we should see them at regular intervals. We went back to our MuVi-SPIM data and corroborated this was the case (5/13)
March 17, 2025 at 5:21 PM
If these protruding cells of the trunks adhered to tendon cells, we should see them at regular intervals. We went back to our MuVi-SPIM data and corroborated this was the case (5/13)
We noticed that a subset of trunk cells formed protrusions towards the epidermis, and we knew the epidermis was stretching dorsally during the stages we were looking at, so we wondered if the two processes could be coupled and if there was contact between the two (3/13)
March 17, 2025 at 5:21 PM
We noticed that a subset of trunk cells formed protrusions towards the epidermis, and we knew the epidermis was stretching dorsally during the stages we were looking at, so we wondered if the two processes could be coupled and if there was contact between the two (3/13)
However, we felt there was an unanswered question here: The dorsal trunks, how do they reach the dorsal side if they are formed on the sides? You can see this movement in this video we did with @microeos.bsky.social (2/13)
March 17, 2025 at 5:21 PM
However, we felt there was an unanswered question here: The dorsal trunks, how do they reach the dorsal side if they are formed on the sides? You can see this movement in this video we did with @microeos.bsky.social (2/13)