Yogesh Gupta
@ykgupta.bsky.social
Scientist at University of Texas Health San Antonio, investigating RNA modifications and chromatin remodeling in pediatric cancers and infectious diseases
https://gccri.uthscsa.edu/lab/gupta/
https://gccri.uthscsa.edu/lab/gupta/
Our study, published today, reveals how nsp16 and nsp10 assemble on mRNA to regulate 2'-O-methylation, a chemical mark that RNA viruses use to evade the host immune restriction. Thanks to @niaidnews.bsky.social for supporting this research. #RNAmodifications
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Structural insights into the assembly and regulation of 2′-O RNA methylation by SARS-CoV-2 nsp16/nsp10
2′-O-ribose methylation of the first transcribed base (adenine or A1 in SARS-CoV-2) of viral RNA mimics host RNAs and subverts the innate immune respo…
www.sciencedirect.com
April 11, 2025 at 4:50 PM
Our study, published today, reveals how nsp16 and nsp10 assemble on mRNA to regulate 2'-O-methylation, a chemical mark that RNA viruses use to evade the host immune restriction. Thanks to @niaidnews.bsky.social for supporting this research. #RNAmodifications
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...