Yewon Han
yewonhan.bsky.social
Yewon Han
@yewonhan.bsky.social
Integrated Ph.D. program at Steinegger Lab
@martinsteinegger.bsky.social
Majored in Bioscience at @Seoul National University
Reposted by Yewon Han
Today @yewonhan.bsky.social will give a flash talk about our metagenomic large-scale protein structure clustering and analysis at #RECOMB2025.

Today (April 29) 1 p.m. at Global Lounge in “The Commons”
AFESM: a metagenomic guide through the protein structure universe! We clustered 821M structures (AFDB&ESMatlas) into 5.12M groups; revealing biome-specific groups, only 1 new fold even after AlphaFold2 re-prediction & many novel domain combos. 🧵
🌐 afesm.foldseek.com
📄 www.biorxiv.org/content/10.1...
April 29, 2025 at 1:08 AM
Reposted by Yewon Han
AFESM: a metagenomic guide through the protein structure universe! We clustered 821M structures (AFDB&ESMatlas) into 5.12M groups; revealing biome-specific groups, only 1 new fold even after AlphaFold2 re-prediction & many novel domain combos. 🧵
🌐 afesm.foldseek.com
📄 www.biorxiv.org/content/10.1...
April 27, 2025 at 12:13 AM