Xin Lai
@xin-lai.bsky.social
I am the PI of the Systems and Network Medicine Laboratory at Tampere University, Finland. We develop bioinformatics and biomathematic methods for analyzing and modelling multimodal data in biomedicine.
Lab website: https://sites.google.com/view/lai-lab.
Lab website: https://sites.google.com/view/lai-lab.
🧬 Just wrapped up ISBRA2025 in Helsinki (@helsinki.fi) with Dr. Jing Tang! Our 21st International Conference on #Bioinformatics Research drew 167 submissions from researchers worldwide. After rigorous review, 66 exceptional papers made it into LNBI proceedings.
link.springer.com/book/10.1007...
link.springer.com/book/10.1007...
August 10, 2025 at 7:50 PM
🧬 Just wrapped up ISBRA2025 in Helsinki (@helsinki.fi) with Dr. Jing Tang! Our 21st International Conference on #Bioinformatics Research drew 167 submissions from researchers worldwide. After rigorous review, 66 exceptional papers made it into LNBI proceedings.
link.springer.com/book/10.1007...
link.springer.com/book/10.1007...
We reconstruct a complex #microRNA network that cross-talks with #SOX10 and #MITF to regulate #tumor plasticity. Network analysis shows miRNA-mediated circuits control signaling pathways - driving phenotype switching, stemness & therapy resistance in #melanoma.
doi.org/10.1002/ijc....
doi.org/10.1002/ijc....
SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity
Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcript....
doi.org
July 7, 2025 at 12:10 PM