Wouter Zandee
wzandee.bsky.social
Wouter Zandee
@wzandee.bsky.social
Endocrinologist @UMCG, Groningen. Endocrine oncology when at work. Kids and sport when at home.
So with a restrictive strategy the likelihood of finding a low-risk thyroid cancer is lower and endocrinologists should be aware of this in the diagnostic phase.
However, when after proper diagnostics low risk thyroid cancer is confirmed: a hemithyreoidectomy is still safe

doi.org/10.1007/s002...
Thyroid Lobectomy for Low‐Risk 1–4 CM Papillary Thyroid Cancer is not Associated with Increased Recurrence Rates in the Dutch Population with a Restricted Diagnostic Work‐Up
Introduction The 2015 American Thyroid Association guidelines recommend to de-escalate treatment such as Thyroid lobectomy instead of total thyroidectomy for 1–4 cm papillary thyroid cancer (PTC). D...
doi.org
December 29, 2024 at 8:09 PM
A second study from the Erasmus MC comparing Germany and the Netherlands demostrated that the incidence of lymph node metastases is also higher in the remaining patients with thyroid cancer (don't forget the selection from the restrictive diagnostic strategy).

doi.org/10.1093/ejen...
Tumor size and presence of metastases in differentiated thyroid cancer: comparing cohorts from two countries
AbstractObjective. Incidence of thyroid cancer varies widely, even across neighboring countries. Data on this phenomenon are largely lacking but are likely
doi.org
December 29, 2024 at 8:06 PM
With a restrictive diagnostic strategy the incidence of thyroid cancer in the NL is low, without an increase in thyroid cancer mortality.

But, the among the remaining patients the incidence of advanced tumors is higher (doi.org/10.1002/wjs....)
December 29, 2024 at 8:02 PM
You adres an important issue. I performed an extensive review of pathology reports several years ago (pubmed.ncbi.nlm.nih.gov/31995804/). And a significant number of tumors with NED were named NEC or NET by non experts. Hope it’s better now.
Importance of Complete Pathology Reporting for Neuroendocrine Carcinoma: WHO Guidelines Are a Good Start but Not Enough - PubMed
Implementation of the WHO 2010 guideline is associated with a significant increase in reporting parameters needed for classification. Stratification of patients is more reliable based on reports conta...
pubmed.ncbi.nlm.nih.gov
November 17, 2024 at 4:44 AM