WntUK
@wntuk.bsky.social
A network of UK based research groups with interests in the structural, molecular and cellular mechanisms of Wnt signalling in development and disease.
And that’s a wrap! @michaelranes.bsky.social draws a highly enjoyable, well organised and stimulating 2nd WNTUK meeting to a close, followed by drinks in the sun in front of a beautiful Worcester College lawn. See you next year!
#WNTUK2025
#WNTUK2025
March 24, 2025 at 6:08 PM
And that’s a wrap! @michaelranes.bsky.social draws a highly enjoyable, well organised and stimulating 2nd WNTUK meeting to a close, followed by drinks in the sun in front of a beautiful Worcester College lawn. See you next year!
#WNTUK2025
#WNTUK2025
Congratulations to @eoghanjm.bsky.social from @ox.ac.uk on winning best talk, and Kieran Hodson from the Toby Phesse group at @cardiffuni.bsky.social @ecscri.bsky.social on winning best poster!
#WNTUK2025
#WNTUK2025
March 24, 2025 at 6:06 PM
Congratulations to @eoghanjm.bsky.social from @ox.ac.uk on winning best talk, and Kieran Hodson from the Toby Phesse group at @cardiffuni.bsky.social @ecscri.bsky.social on winning best poster!
#WNTUK2025
#WNTUK2025
The final talk of the day is our international keynote speaker @michaelboutros.bsky.social from @dkfz.bsky.social @uniheidelberg.bsky.social presenting a past and present overview on mechanisms of Wnt signal transduction.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 4:17 PM
The final talk of the day is our international keynote speaker @michaelboutros.bsky.social from @dkfz.bsky.social @uniheidelberg.bsky.social presenting a past and present overview on mechanisms of Wnt signal transduction.
#WNTUK2025
#WNTUK2025
The penultimate talk of the day is our best selected PhD talk by Dr Ben Broadway from the Guettler lab at @icr.ac.uk presenting on CRISPR approaches to uncovering new tankyrase regulatory mechanisms in Wnt/B-catenin signalling.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 4:02 PM
The penultimate talk of the day is our best selected PhD talk by Dr Ben Broadway from the Guettler lab at @icr.ac.uk presenting on CRISPR approaches to uncovering new tankyrase regulatory mechanisms in Wnt/B-catenin signalling.
#WNTUK2025
#WNTUK2025
Many thanks WntUK ECR rep @nadianasreddin.bsky.social from @cruk-si.bsky.social for chairing the Future Generation session!
#WNTUK2025
#WNTUK2025
March 24, 2025 at 3:45 PM
Many thanks WntUK ECR rep @nadianasreddin.bsky.social from @cruk-si.bsky.social for chairing the Future Generation session!
#WNTUK2025
#WNTUK2025
The final session of the day is a Future Generation focus starting with invited ECR speaker Dr Yeonjoo Kim from the @ianmcgough.bsky.social group at @babrahaminst.bsky.social presenting on a novel RASopathy caused by hyperactive non-canonical Wnt signalling.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 3:37 PM
The final session of the day is a Future Generation focus starting with invited ECR speaker Dr Yeonjoo Kim from the @ianmcgough.bsky.social group at @babrahaminst.bsky.social presenting on a novel RASopathy caused by hyperactive non-canonical Wnt signalling.
#WNTUK2025
#WNTUK2025
Final talk of the disease session is a selected abstract from Nico Mueller of the de la Roche group at @cambridgeuni.bsky.social @cruk-ci.bsky.social speaking about novel LGR5 immunotherapeutics against multiple cancer types.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 2:49 PM
Final talk of the disease session is a selected abstract from Nico Mueller of the de la Roche group at @cambridgeuni.bsky.social @cruk-ci.bsky.social speaking about novel LGR5 immunotherapeutics against multiple cancer types.
#WNTUK2025
#WNTUK2025
Next up another selected abstract this time from Dr Nuray Gunduz at the Sansom group at @cruk-si.bsky.social presenting her research on LGR4 maintenance of intestinal homeostasis and protection from mutant-cell clonal expansion.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 2:38 PM
Next up another selected abstract this time from Dr Nuray Gunduz at the Sansom group at @cruk-si.bsky.social presenting her research on LGR4 maintenance of intestinal homeostasis and protection from mutant-cell clonal expansion.
#WNTUK2025
#WNTUK2025
Many thanks to @yatlasi.bsky.social from @qubelfastofficial.bsky.social for chairing the Disease and Translational Research session.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 2:22 PM
Many thanks to @yatlasi.bsky.social from @qubelfastofficial.bsky.social for chairing the Disease and Translational Research session.
#WNTUK2025
#WNTUK2025
The Disease & Translational Research session begins with invited speaker Dr @vivianlilab.bsky.social from @crick.ac.uk presenting on SOX2 driven fetal reprogramming and reversible dormancy in colorectal cancer.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 2:13 PM
The Disease & Translational Research session begins with invited speaker Dr @vivianlilab.bsky.social from @crick.ac.uk presenting on SOX2 driven fetal reprogramming and reversible dormancy in colorectal cancer.
#WNTUK2025
#WNTUK2025
Lunch break means it’s WntUK poster time!
We have 17 fabulous posters here today covering Wnt signalling across mechanisms, development and disease from all career stages.
#WNTUK2025
We have 17 fabulous posters here today covering Wnt signalling across mechanisms, development and disease from all career stages.
#WNTUK2025
March 24, 2025 at 2:03 PM
Lunch break means it’s WntUK poster time!
We have 17 fabulous posters here today covering Wnt signalling across mechanisms, development and disease from all career stages.
#WNTUK2025
We have 17 fabulous posters here today covering Wnt signalling across mechanisms, development and disease from all career stages.
#WNTUK2025
We’ve paused for a glorious lunch break!
March 24, 2025 at 1:50 PM
We’ve paused for a glorious lunch break!
The final session before lunch is a selected abstract from Lee Placito Fellow of GI Cancer @eoghanjm.bsky.social from the @leedham-simon.bsky.social group at @ox.ac.uk speaking about GREMLIN1 role in stromal remodelling of Wnt-dependent ectopic stem niches in the intestine.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 1:37 PM
The final session before lunch is a selected abstract from Lee Placito Fellow of GI Cancer @eoghanjm.bsky.social from the @leedham-simon.bsky.social group at @ox.ac.uk speaking about GREMLIN1 role in stromal remodelling of Wnt-dependent ectopic stem niches in the intestine.
#WNTUK2025
#WNTUK2025
Taking us into the afternoon is the third selected abstract from Dr Ines Alvarez Rodrigo from the @jpvincentlab.bsky.social at the @crick.ac.uk presenting her research on Wnt secretion mechanisms at the membrane.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 12:12 PM
Taking us into the afternoon is the third selected abstract from Dr Ines Alvarez Rodrigo from the @jpvincentlab.bsky.social at the @crick.ac.uk presenting her research on Wnt secretion mechanisms at the membrane.
#WNTUK2025
#WNTUK2025
Many thanks to Dr Florencia Cavodeassi from @citystgeorges.bsky.social for chairing the Wnt Signalling in Development session.
#WNT2025
#WNT2025
March 24, 2025 at 12:04 PM
Many thanks to Dr Florencia Cavodeassi from @citystgeorges.bsky.social for chairing the Wnt Signalling in Development session.
#WNT2025
#WNT2025
We are incredibly grateful to our kind sponsors for the day @thermofishersci.bsky.social @biologists.bsky.social @oxfordcancer.bsky.social and @cambridgebio.bsky.social
#WNTUK2025
#WNTUK2025
March 24, 2025 at 11:53 AM
We are incredibly grateful to our kind sponsors for the day @thermofishersci.bsky.social @biologists.bsky.social @oxfordcancer.bsky.social and @cambridgebio.bsky.social
#WNTUK2025
#WNTUK2025
Our invited speaker for the Wnt Signalling in Development session is Prof Denis Headon from @cmvm-edinburghuni.bsky.social presenting on Wnt signalling patterning of the Whisker Array.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 11:46 AM
Our invited speaker for the Wnt Signalling in Development session is Prof Denis Headon from @cmvm-edinburghuni.bsky.social presenting on Wnt signalling patterning of the Whisker Array.
#WNTUK2025
#WNTUK2025
The final talk of the morning session is a selected abstract from our international guests! Dr Michaela Holzem from @michaelboutros.bsky.social lab at @dkfz.bsky.social @uniheidelberg.bsky.social presents on PI3K regulation of Wg secretion in polarised tissue.
All welcome at WntUK!
#WNTUK2025
All welcome at WntUK!
#WNTUK2025
March 24, 2025 at 11:01 AM
The final talk of the morning session is a selected abstract from our international guests! Dr Michaela Holzem from @michaelboutros.bsky.social lab at @dkfz.bsky.social @uniheidelberg.bsky.social presents on PI3K regulation of Wg secretion in polarised tissue.
All welcome at WntUK!
#WNTUK2025
All welcome at WntUK!
#WNTUK2025
Our first selected oral presentation comes from Elisabeth Chapman from the @melissa-gammons1.bsky.social group at the CIMR @thecimr.bsky.social telling us about her research into casein kinase 1 regulation of Wnt signalosome assembly.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 10:45 AM
Our first selected oral presentation comes from Elisabeth Chapman from the @melissa-gammons1.bsky.social group at the CIMR @thecimr.bsky.social telling us about her research into casein kinase 1 regulation of Wnt signalosome assembly.
#WNTUK2025
#WNTUK2025
Many thanks to @matthias-krause.bsky.social from @kingscollegelondon.bsky.social for chairing the first session on Molecular Mechanisms of Wnt Signal Transduction.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 10:29 AM
Many thanks to @matthias-krause.bsky.social from @kingscollegelondon.bsky.social for chairing the first session on Molecular Mechanisms of Wnt Signal Transduction.
#WNTUK2025
#WNTUK2025
The invited speaker for the opening Molecular Mechanisms of Wnt Signalling session is fellow conference organiser Prof Yvonne Jones from Nuffield Dept of Medicine Div of Structural Biology @ox.ac.uk revealing Structural insights into the extracellular modulation of Wnt signalling
#WNTUK2025
#WNTUK2025
March 24, 2025 at 10:12 AM
The invited speaker for the opening Molecular Mechanisms of Wnt Signalling session is fellow conference organiser Prof Yvonne Jones from Nuffield Dept of Medicine Div of Structural Biology @ox.ac.uk revealing Structural insights into the extracellular modulation of Wnt signalling
#WNTUK2025
#WNTUK2025
Conference organiser and WntUK committee member @michaelranes.bsky.social from @ox.ac.uk @oxfordbiochemistry.bsky.social welcomes attendees and opens the meeting.
#WNTUK2025
#WNTUK2025
March 24, 2025 at 10:07 AM
Conference organiser and WntUK committee member @michaelranes.bsky.social from @ox.ac.uk @oxfordbiochemistry.bsky.social welcomes attendees and opens the meeting.
#WNTUK2025
#WNTUK2025
#WNT2025 is here! Safe journey to all our attendees en route to Worcester College at @ox.ac.uk this morning.
We’ve a fantastic programme of research talks and posters showcasing the best of UK Wnt research and the scientists behind it!
Follow here for live updates through the day.
We’ve a fantastic programme of research talks and posters showcasing the best of UK Wnt research and the scientists behind it!
Follow here for live updates through the day.
March 24, 2025 at 6:04 AM
Welcome to #2 of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!
Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025
Yeon's Quickfire Q&A below 🧵1/
Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025
Yeon's Quickfire Q&A below 🧵1/
February 5, 2025 at 10:08 PM
Welcome to #2 of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!
Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025
Yeon's Quickfire Q&A below 🧵1/
Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025
Yeon's Quickfire Q&A below 🧵1/
Here's the very first of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!
First up is Dr @nadianasreddin.bsky.social PostDoc in the
Owen Sansom lab at @cruk-si.bsky.social and ECR rep on the WntUK committee
Here's Nadia's QuickFire Q&A below 🧵1/
First up is Dr @nadianasreddin.bsky.social PostDoc in the
Owen Sansom lab at @cruk-si.bsky.social and ECR rep on the WntUK committee
Here's Nadia's QuickFire Q&A below 🧵1/
December 17, 2024 at 5:42 PM
Here's the very first of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!
First up is Dr @nadianasreddin.bsky.social PostDoc in the
Owen Sansom lab at @cruk-si.bsky.social and ECR rep on the WntUK committee
Here's Nadia's QuickFire Q&A below 🧵1/
First up is Dr @nadianasreddin.bsky.social PostDoc in the
Owen Sansom lab at @cruk-si.bsky.social and ECR rep on the WntUK committee
Here's Nadia's QuickFire Q&A below 🧵1/