James Deardorff
wjdeardorff.bsky.social
James Deardorff
@wjdeardorff.bsky.social
Geriatrician and research faculty at UCSF. Former UCSF Geriatrics clinical and T32 aging research fellow, Duke IM resident, and SLU med student.
"Managing Hypercholesterolemia in Adults Older Than 75 years Without a History of Atherosclerotic Cardiovascular Disease: An Expert Clinical Consensus From the National Lipid Association and the American Geriatrics Society" (JAGS 2025) - agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
April 11, 2025 at 7:04 PM
"A Person-Centered Approach to Supplemental Oxygen Therapy in the Outpatient Setting" (JAMA IM 2025) - "empowers patients, improves QOL, increases adherence, emphasizes safety, individualizes tx approaches, & weighs risks/benefits to prioritize patient/family goals" - jamanetwork.com/journals/jam...
April 7, 2025 at 9:23 PM
"Escitalopram for agitation in Alzheimer’s dementia: a randomized controlled phase 3 trial" (2025) - "Clinicians need to be cautious in recommending escitalopram as an alternative to citalopram for this condition." - www.nature.com/articles/s41...
March 28, 2025 at 12:08 AM
"Management of Diabetes and Hyperglycemia in the Hospital: A Systematic Review of Clinical Practice Guidelines" (2025) - diabetesjournals.org/care/article...
March 25, 2025 at 7:58 PM
"Frailty Matters—Why Isn't It Guiding Clinical Decisions?" (JAGS 2025) "A shift from age- and disease-based to frailty-informed and comprehensive care presents an opportunity for improvement. Still, its implementation must be guided by evidence" - agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
March 25, 2025 at 12:17 AM
"Addressing Both Racism and Ageism in Research—An Opportunity for MOSAAIC" (JAMA IM 2025) - Exclusion of older people—especially individuals who are less able to advocate for themselves—is analogous to making a population invisible - jamanetwork.com/journals/jam...
February 24, 2025 at 8:35 PM
"2025 American Society of Anesthesiologists Practice Advisory for Perioperative Care of Older Adults Scheduled for Inpatient Surgery" - clinical recommendations on perioperative anesthesia care in older adults to minimize adverse cognitive outcomes - journals.lww.com/anesthesiolo...
February 20, 2025 at 12:50 AM
"Uncertainty of risk estimates from clinical prediction models: rationale, challenges, and approaches" (BMJ 2025) - "Most models only allow a single point estimate of risk to be calculated; however, providing the associated uncertainty gives a more complete picture" - www.bmj.com/content/388/...
February 13, 2025 at 5:10 PM
"Around the EQUATOR With Clin-STAR: AI-Based RCT Challenges & Opportunities in Aging Research" (JAGS 2025) - Researchers should adopt a conceptual framework designed around the 5Ms (Mind, Mobility, Medications, Matters most, & Multi-complexity) - agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
February 10, 2025 at 3:26 PM
"Updating STEADI for Primary Care: Recommendations From the American Geriatrics Society Workgroup" (JAGS 2025) - "The proposed additional assessments address the multifactorial nature of falls, ultimately enhancing fall prevention efforts." - agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
January 30, 2025 at 9:16 PM
D-CARE and IN-PEACE randomized clinical trials for persons with dementia (JAMA 2025) - "Despite the disappointing results, we must continue to innovate and find ways to improve care because the challenges caused by dementia remain"

jamanetwork.com/journals/jam...

jamanetwork.com/journals/jam...
January 29, 2025 at 6:10 PM
"Avoiding causal fraud in the evaluation of clinical benefits of treatments for Alzheimer's disease" (A&D 2025) - "The average between-group diff. in score change is where the debate should be focused to contextualize clinical meaningfulness." - alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
January 29, 2025 at 3:24 PM
"Screening for Osteoporosis to Prevent Fractures: A Systematic Evidence Review for the US Preventive Services Task Force" (JAMA 2025) - "USPSTF recommends screening for osteoporosis to prevent osteoporotic fractures in women 65 years or older (B recommendation)" - jamanetwork.com/journals/jam...
January 23, 2025 at 6:02 PM