William Sessions
@william.maxoutput.ai
Creating clinical research site automations. CEO & Co-Founder @MaxOutput. Building systems that eliminate the manual chaos site staff deal with daily.
Pinned
I've been a yacht deckhand, an SDR who 6x'd the sales record, and a CEO of a hardware startup. Now I build automation for clinical research sites. The through-line? Systems thinking. (1/4)
Spent the morning teaching Sarah a few n8n workflow over hot cocoa.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
December 27, 2025 at 4:27 AM
Spent the morning teaching Sarah a few n8n workflow over hot cocoa.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Grateful for the humans who made this year worth it.
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
December 25, 2025 at 1:07 AM
Grateful for the humans who made this year worth it.
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
To everyone in clinical research working through the holidays: your work matters more than most people realize.
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
December 23, 2025 at 9:47 AM
To everyone in clinical research working through the holidays: your work matters more than most people realize.
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Most site managers are one resignation away from chaos, because every process lives in someone's head.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
December 22, 2025 at 7:24 PM
Most site managers are one resignation away from chaos, because every process lives in someone's head.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Holidays are stressful for CRCs: 'queries don't stop.' Urgency feels productive.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
December 21, 2025 at 3:30 PM
Holidays are stressful for CRCs: 'queries don't stop.' Urgency feels productive.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
Protocol amnesia costs you 15 minutes per patient visit.
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
December 20, 2025 at 8:30 PM
Protocol amnesia costs you 15 minutes per patient visit.
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Many site coordinators I talk to eat lunch at their desk.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
December 19, 2025 at 7:08 PM
Many site coordinators I talk to eat lunch at their desk.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
Most CRCs spend 15-20 min/visit updating CTMS. That's 6+ hours/week of admin.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
December 18, 2025 at 8:02 PM
Most CRCs spend 15-20 min/visit updating CTMS. That's 6+ hours/week of admin.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
The "always available" CRC culture isn't dedication - it's a systems failure.
Boundaries aren't laziness. They're strategic. Protected time = fewer errors, faster closeout, better retention.
Boundaries aren't laziness. They're strategic. Protected time = fewer errors, faster closeout, better retention.
December 17, 2025 at 7:43 PM
The "always available" CRC culture isn't dedication - it's a systems failure.
Boundaries aren't laziness. They're strategic. Protected time = fewer errors, faster closeout, better retention.
Boundaries aren't laziness. They're strategic. Protected time = fewer errors, faster closeout, better retention.
If everything is a priority, nothing is.
Your site's drowning in "urgent" tasks because you haven't defined what urgent actually means.
I spent years in sales watching reps spiral. The fix? A simple triage system.
Your site's drowning in "urgent" tasks because you haven't defined what urgent actually means.
I spent years in sales watching reps spiral. The fix? A simple triage system.
If everything is a priority, nothing is.
Your sit
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December 16, 2025 at 1:51 PM
If everything is a priority, nothing is.
Your site's drowning in "urgent" tasks because you haven't defined what urgent actually means.
I spent years in sales watching reps spiral. The fix? A simple triage system.
Your site's drowning in "urgent" tasks because you haven't defined what urgent actually means.
I spent years in sales watching reps spiral. The fix? A simple triage system.
I started learning automation to solve the problems that my wife lived as an RC.
What surprised me most: the gap between "this would save 12 hours a week" and "but we've always done it this way."
The tech isn't hard. Changing systems thinking is.
#ClinicalResearch
What surprised me most: the gap between "this would save 12 hours a week" and "but we've always done it this way."
The tech isn't hard. Changing systems thinking is.
#ClinicalResearch
December 15, 2025 at 2:57 PM
I started learning automation to solve the problems that my wife lived as an RC.
What surprised me most: the gap between "this would save 12 hours a week" and "but we've always done it this way."
The tech isn't hard. Changing systems thinking is.
#ClinicalResearch
What surprised me most: the gap between "this would save 12 hours a week" and "but we've always done it this way."
The tech isn't hard. Changing systems thinking is.
#ClinicalResearch
Everyone's predicting 2026 clinical research trends.
Mine? Sites that build operational moats - unique data capabilities, specialized communities, AI workflows - finally get leverage.
What's your prediction? #ClinicalResearch
Mine? Sites that build operational moats - unique data capabilities, specialized communities, AI workflows - finally get leverage.
What's your prediction? #ClinicalResearch
December 14, 2025 at 2:38 PM
Everyone's predicting 2026 clinical research trends.
Mine? Sites that build operational moats - unique data capabilities, specialized communities, AI workflows - finally get leverage.
What's your prediction? #ClinicalResearch
Mine? Sites that build operational moats - unique data capabilities, specialized communities, AI workflows - finally get leverage.
What's your prediction? #ClinicalResearch
Every efficient site I've worked with protects their team's time like it's sacred.
The struggling ones? Drowning in 20+ systems, reactive queries, sponsor tech that doesn't integrate.
What's your team's biggest time waster? #ClinicalResearch
The struggling ones? Drowning in 20+ systems, reactive queries, sponsor tech that doesn't integrate.
What's your team's biggest time waster? #ClinicalResearch
December 13, 2025 at 1:34 PM
Every efficient site I've worked with protects their team's time like it's sacred.
The struggling ones? Drowning in 20+ systems, reactive queries, sponsor tech that doesn't integrate.
What's your team's biggest time waster? #ClinicalResearch
The struggling ones? Drowning in 20+ systems, reactive queries, sponsor tech that doesn't integrate.
What's your team's biggest time waster? #ClinicalResearch
Building workflows for CRCs this week.
Every conversation: more respect for the complexity they juggle.
61% of their time is admin work. 66% believe tech could help.
But most tech just adds another system to the pile.
We're fixing that.
#ClinicalResearch #CRC
Every conversation: more respect for the complexity they juggle.
61% of their time is admin work. 66% believe tech could help.
But most tech just adds another system to the pile.
We're fixing that.
#ClinicalResearch #CRC
December 12, 2025 at 2:38 PM
Building workflows for CRCs this week.
Every conversation: more respect for the complexity they juggle.
61% of their time is admin work. 66% believe tech could help.
But most tech just adds another system to the pile.
We're fixing that.
#ClinicalResearch #CRC
Every conversation: more respect for the complexity they juggle.
61% of their time is admin work. 66% believe tech could help.
But most tech just adds another system to the pile.
We're fixing that.
#ClinicalResearch #CRC
51% screen failure rate isn't a recruitment problem - it's a pre-screening problem.
Most sites burn CRC hours on patients who were never eligible. Better intake = fewer wasted visits, happier patients, better enrollment.
#ClinicalResearch
Most sites burn CRC hours on patients who were never eligible. Better intake = fewer wasted visits, happier patients, better enrollment.
#ClinicalResearch
December 11, 2025 at 6:26 PM
51% screen failure rate isn't a recruitment problem - it's a pre-screening problem.
Most sites burn CRC hours on patients who were never eligible. Better intake = fewer wasted visits, happier patients, better enrollment.
#ClinicalResearch
Most sites burn CRC hours on patients who were never eligible. Better intake = fewer wasted visits, happier patients, better enrollment.
#ClinicalResearch
Portal fatigue isn't a training problem.
You don't need better users. You need fewer systems with actual integration.
Sites drowning in 15 logins don't need another tutorial - they need automation that bridges the gaps.
Technology should reduce cognitive load, not multiply it.
You don't need better users. You need fewer systems with actual integration.
Sites drowning in 15 logins don't need another tutorial - they need automation that bridges the gaps.
Technology should reduce cognitive load, not multiply it.
December 10, 2025 at 8:58 PM
Portal fatigue isn't a training problem.
You don't need better users. You need fewer systems with actual integration.
Sites drowning in 15 logins don't need another tutorial - they need automation that bridges the gaps.
Technology should reduce cognitive load, not multiply it.
You don't need better users. You need fewer systems with actual integration.
Sites drowning in 15 logins don't need another tutorial - they need automation that bridges the gaps.
Technology should reduce cognitive load, not multiply it.
Burnout isn't a badge of honor - it's a systems failure.
44% of CRCs report emotional exhaustion. That's not a self-care problem. That's a workflow problem.
Learn more here: open.substack.com/pub/maxoutpu...
#ClinicalResearch
44% of CRCs report emotional exhaustion. That's not a self-care problem. That's a workflow problem.
Learn more here: open.substack.com/pub/maxoutpu...
#ClinicalResearch
December 9, 2025 at 6:50 PM
Burnout isn't a badge of honor - it's a systems failure.
44% of CRCs report emotional exhaustion. That's not a self-care problem. That's a workflow problem.
Learn more here: open.substack.com/pub/maxoutpu...
#ClinicalResearch
44% of CRCs report emotional exhaustion. That's not a self-care problem. That's a workflow problem.
Learn more here: open.substack.com/pub/maxoutpu...
#ClinicalResearch
76% of trials now get amended. Sites operate under mixed protocol versions for 7 months on average.
That's not a staffing problem. That's a systems problem.
Before you add headcount, ask: what work shouldn't exist at all? You can't hire your way out of bad systems.
That's not a staffing problem. That's a systems problem.
Before you add headcount, ask: what work shouldn't exist at all? You can't hire your way out of bad systems.
December 8, 2025 at 10:28 PM
76% of trials now get amended. Sites operate under mixed protocol versions for 7 months on average.
That's not a staffing problem. That's a systems problem.
Before you add headcount, ask: what work shouldn't exist at all? You can't hire your way out of bad systems.
That's not a staffing problem. That's a systems problem.
Before you add headcount, ask: what work shouldn't exist at all? You can't hire your way out of bad systems.
I've been a yacht deckhand, an SDR who 6x'd the sales record, and a CEO of a hardware startup. Now I build automation for clinical research sites. The through-line? Systems thinking. (1/4)
December 8, 2025 at 4:19 AM
I've been a yacht deckhand, an SDR who 6x'd the sales record, and a CEO of a hardware startup. Now I build automation for clinical research sites. The through-line? Systems thinking. (1/4)