Inhibiting cytoneme formation prevents niche contact and BMP signal reactivation thus blocking germ cell dedifferentiation

A new in vitro model also illustrates how a source of BMP can promote cytoneme contact for signal activation

Now we have found that during germ cell dedifferentiation to reoccupy an empty niche, cytoneme formation becomes polarised toward the niche enabling access to stemness-promoting BMP signalling

First post, first Postdoc paper, first 🦓🐟 paper, first journal cover! 🥳

🎶On the fourth day of Christmas, Dev Cell gave to me: An improved Erk biosensor that detects oscillatory Erk dynamics driven by mitotic erasure during early development🎶

www.cell.com/developmenta...