Isabel Conze
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whizzybrains.bsky.social
Isabel Conze
@whizzybrains.bsky.social
Working with C. elegans to understand the control of appetite and feeding behaviour - Schafer Lab at the MRC Laboratory of Molecular Biology, Cambridge.
Reposted by Isabel Conze
The latest from Schafer lab: @lariferg.bsky.social, collaborating with Beets lab, uses Alphafold multimer and deep learning to predict GPCR peptide ligands www.biorxiv.org/content/10.1...
DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active state complexes and deep learning embeddings
G protein-coupled receptors (GPCRs) are important cell surface receptors involved in numerous physiological processes. Although peptides are the cognate ligands for many of these receptors, identifyin...
www.biorxiv.org
March 21, 2025 at 6:43 AM
Reposted by Isabel Conze
Very excited and proud to finally share this story! 🐙

We discovered surprising roles for dopamine and acetylcholine in the Octopus visual system…
doi.org/10.1101/2025...
Novel dopaminergic neurotransmission in the Octopus visual system
Coleoid cephalopods such as the common octopus have a complex visual system, with a camera-type eye and a large optic lobe, that evolved independently from its counterpart in vertebrates. However, the...
doi.org
April 4, 2025 at 5:04 PM