Nic Wheeler
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wheelerlab.bio
Nic Wheeler
@wheelerlab.bio
Assistant professor of infectious disease.
UW-Eau Claire Biology. Interested in NTDs, helminths, and Chelsea Football Club. Once submitted to Nature.
I am pleased to present a project we've been working on for the least year to try to answer a fundamental question - does a parasite's developmental niche as an egg have effects on larval stages? We show that the answer is very much yes - which has a few implications. www.biorxiv.org/content/10.1...
Tissue-specific distribution of eggs in the definitive host drives transcriptomic and behavioral differences in Schistosoma mansoni miracidia
Schistosomiasis is a neglected tropical disease caused by human-infective schistosomes (Trematoda: Schistosoma). Intestinal schistosomiasis in sub-Saharan Africa and the Neotropics is caused primarily...
www.biorxiv.org
August 21, 2025 at 2:13 PM
Reposted by Nic Wheeler
New research w/ @jacobphd.bsky.social et al. published today in Nature Communications: Genes linked to schistosome resistance identified in a genome-wide association study of African snail vectors doi.org/10.1038/s414... 🐌🪱🧬
Genes linked to schistosome resistance identified in a genome-wide association study of African snail vectors - Nature Communications
A genome wide association study of an African vector of schistosomiasis revealed two genomic regions associated with resistance to Schistosoma mansoni. These findings will inform novel control strateg...
doi.org
July 27, 2025 at 9:42 AM
Very excited and proud to release a project that I’ve been thinking about for at least 7 years, well before I started my faculty position. We built an imaging and computational platform from the ground up to help answer some outstanding questions in schistosome miracidia biology.
Quantitative ethology of schistosome miracidia characterizes a conserved snail peptide that inhibits penetration
Over 700 million people are at risk of contracting schistosomiasis due to regular exposure to freshwater sources where infected snails, the obligate intermediate hosts of schistosomes, are endemic. Al...
www.biorxiv.org
July 3, 2025 at 11:36 PM
Our annual Celebration of Scholarship and Creative Activity is a yearly highlight of mine. Proud of the students and their 5 poster presentations!
April 25, 2025 at 12:17 AM
Such an important resource. Subscribe with me!
Keep VEuPathDB open-access to all by subscribing today! veupathdb.org/veupathdb/ap...
April 23, 2025 at 1:46 AM
UWEC students won an unprecedented three (3!) Goldwater Scholarships this year, and our lab member Rachel was one of them! I’m so proud of Rachel’s development as a scientist and excited that she’s been recognized as a future leader. Check out the story on her award: www.uwec.edu/stories/firs...
From first-gen transfer jitters to Goldwater Scholar: Rachel Horejsi
Rachel Horejsi Goldwater Award
www.uwec.edu
April 8, 2025 at 8:10 PM
Now published at IJP:DDR! www.sciencedirect.com/science/arti...
March 24, 2025 at 1:48 PM
Very excited to release the first project from my lab, an update of wrmXpress with a graphical user interface:

www.biorxiv.org/content/10.1...
A graphical user interface for wrmXpress 2.0 streamlines helminth phenotypic screening
Image-based phenotypic screening is a fundamental technique used to better understand the basic biology of helminths and advance discovery of new anthelmintics. Miniaturization of screening platforms ...
www.biorxiv.org
March 17, 2025 at 9:27 PM
Where were you when the American biomedical research apparatus collapsed?
February 8, 2025 at 12:44 AM
Speaking of Google Chrome…as I do at least once a year, this week I tried to force myself to switch to Safari and yet once again failed because it just isn’t a very good piece of software.
November 21, 2024 at 9:12 PM
Hi everyone! For those of us who have a lab website, it’s simple to use the website domain as your BSKY handle. It’s also possible to provide subdomains for other members of the lab. Checkout their instructions: bsky.social/about/blog/4...
How to set your domain as your handle - Bluesky
Using a domain as your handle helps with account identity, verification, and portability. Here's how to set your domain as your handle.
bsky.social
November 21, 2024 at 1:21 PM
Reposted by Nic Wheeler
Trying to find my way around here. Have created a starter pack for parasitologists. Join, connect and spread the word!
go.bsky.app/5UiPsYr
Parasitologists Unite
Join the conversation
go.bsky.app
November 9, 2024 at 3:23 PM
The best thing about research at a PUI is getting to do whatever I want. Excited to see how 3D printing capabilities broadens the types of experiments we can do.
November 17, 2024 at 1:45 AM