Wertheim UF Scripps
wertheimufscripps.bsky.social
Wertheim UF Scripps
@wertheimufscripps.bsky.social
Researching the molecular basis of health and disease, and working to discocover new treatments for unmet medical needs. Jupiter, FL #UF #GoGators
His talk focused on "adhesion" molecues that bridge synapses.
A discovery from his group is that these genes can have different functions in neurons depending on how they are spliced, and increased "excitation" is one of the factors that can change gene function. Fascinating!
January 31, 2025 at 12:05 AM
Great coverage, thanks Jonathan. Did you happen to see Matt Disney etal's poster on a MYC-riboTAC degrader in multiple myeloma? Great teamwork. www.sciencedirect.com/science/arti...
A Novel Ribonuclease Targeting Small Molecule RNA-Degrader (MYC-RiboTAC) Overcomes MYC Dependency in Multiple Myeloma
c-MYC (MYC) is an important oncogene in multiple myeloma (MM), driving MM cell proliferation, metabolism, and survival. However, MYC has been challeng…
www.sciencedirect.com
December 9, 2024 at 5:17 PM
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December 3, 2024 at 9:42 PM
Structural studies like these require a cryo electron microscope that can visualize things so small it's like seeing a nickel on the face of the moon from your back yard. These structural studies reveal basic biology and the root causes of disease. They also help scientists create new medicines.
December 2, 2024 at 9:26 PM