Will Allen
@weallen1.bsky.social
Biology of homeostasis & resilience. New tools to map + control cells. Asst prof at Stanford Dev Bio. HarvardJunior Fellow, neuro Ph.D. Stanford, MPhil MRC LMB
Reposted by Will Allen
Check out this preprint on Perturb-multi (doi.org/10.1101/2024...), a multi-year collaborative effort that enabled multi-modal in vivo genotype-phenotype mapping by pooled genetic perturbations and high-dimensionality phenotype readout by imaging and sequencing.
bsky.app/profile/weal...
bsky.app/profile/weal...
A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
Organ function requires coordinated activities of thousands of genes in distinct, spatially organized cell types. Understanding the basis of emergent tissue function requires approaches to dissect the...
doi.org
November 25, 2024 at 2:09 AM
Check out this preprint on Perturb-multi (doi.org/10.1101/2024...), a multi-year collaborative effort that enabled multi-modal in vivo genotype-phenotype mapping by pooled genetic perturbations and high-dimensionality phenotype readout by imaging and sequencing.
bsky.app/profile/weal...
bsky.app/profile/weal...
In collaboration with Reuben Saunders, @jswlab.bsky.social, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue.
Check it out!
www.biorxiv.org/content/10.1...
Check it out!
www.biorxiv.org/content/10.1...
A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
Organ function requires coordinated activities of thousands of genes in distinct, spatially organized cell types. Understanding the basis of emergent tissue function requires approaches to dissect the...
www.biorxiv.org
November 21, 2024 at 6:24 PM
In collaboration with Reuben Saunders, @jswlab.bsky.social, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue.
Check it out!
www.biorxiv.org/content/10.1...
Check it out!
www.biorxiv.org/content/10.1...