Vikram Alva
@vikramalva.bsky.social
Departmental Group Leader - Protein Bioinformatics @ Max Planck Institute for Biology - Tübingen @mpi-bio-fml.bsky.social
Protein evolution // MPI Bioinformatics Toolkit // prokaryotic cell-surface proteins // prokaryotic histones
Protein evolution // MPI Bioinformatics Toolkit // prokaryotic cell-surface proteins // prokaryotic histones
Our Pyrodictium cannulae paper is out in its final form! Cannulae assemble into calcium-stabilized tubular filaments stable at 100 °C—a unique archaeal cell–cell connection. Led brilliantly by @mikesleutel.bsky.social & @vinceconticello.bsky.social.
www.nature.com/articles/s41467-025-64120-8
www.nature.com/articles/s41467-025-64120-8
October 14, 2025 at 2:25 PM
Our Pyrodictium cannulae paper is out in its final form! Cannulae assemble into calcium-stabilized tubular filaments stable at 100 °C—a unique archaeal cell–cell connection. Led brilliantly by @mikesleutel.bsky.social & @vinceconticello.bsky.social.
www.nature.com/articles/s41467-025-64120-8
www.nature.com/articles/s41467-025-64120-8
We hope this study advances our understanding of chromatin evolution, genome compaction, and the emergence of DNA packaging strategies in prokaryotes.
May 12, 2025 at 9:17 AM
We hope this study advances our understanding of chromatin evolution, genome compaction, and the emergence of DNA packaging strategies in prokaryotes.
Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1...
@mpi-bio-fml.bsky.social
@mpi-bio-fml.bsky.social
May 12, 2025 at 9:17 AM
Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1...
@mpi-bio-fml.bsky.social
@mpi-bio-fml.bsky.social
Excited to see this beautiful work from @bupbuse.bsky.social and @tbharat-lab.bsky.social now out in @plosbiology.org!
It maps the ultrastructural topology of the C. glutamicum cell surface, including its patchy S-layer. Delighted to be part of this story.
It maps the ultrastructural topology of the C. glutamicum cell surface, including its patchy S-layer. Delighted to be part of this story.
April 23, 2025 at 2:32 PM
Excited to see this beautiful work from @bupbuse.bsky.social and @tbharat-lab.bsky.social now out in @plosbiology.org!
It maps the ultrastructural topology of the C. glutamicum cell surface, including its patchy S-layer. Delighted to be part of this story.
It maps the ultrastructural topology of the C. glutamicum cell surface, including its patchy S-layer. Delighted to be part of this story.