Definitely not one of these. Very familiar with the first 2 and reading about the third it's not sounding familiar.

Alas, not one of these. What I remember was a nanotech disease that allowed people to grow hidden shock tentacles or turn into a T-1000esque liquid metal, or sense emotions, or a few other powers. Definitely a focus on late teens early 20s resistance to control.

Mass Effect series. Fallout 4. Neverwinter Nights 1 & 2, Pathfinder Wrath of the Righteous. Slay the Princess. Cyberpunk 2077. City of Heroes. Dynasty Warriors. Dishonored. Signalis.

My first non DnD game was some kind of cyberpunk dystopian thing circa 91. I don't remember the name or setting though which makes me kind of sad.