Big shoutout to @rosswaller.bsky.social @nicolas3474.bsky.social and the man of the hour @scottchisholm.bsky.social
7/7

And with that, we can start pushing the snowball so that people can select new drug targets, vaccine candidates, or simply better understand how malaria works.
6/7

It's funny how we can summarise years of hard work in some scatter-, bar- and box-plots, but those plots tell an amazing story, a story on how we pushed the genome annotation of Plasmodium with 1600 proteins now spatially resolved.
5/7

And just like that we ended up doing tons of analysis about everything: from evolutionary profiles, to physico-chemical properties, to 3D structure analysis, to functional annotations and everything in between. The next part was to conduct exhaustive statistical testing.
4/7

We needed to make sense of all the data we had, Scott told me: "can you help me with X, Y & Z", to which I said: "Of course man, no problemo".
3/7

Credit where credit is due, @scottchisholm.bsky.social optimised the procedure to obtain P. falciparum schizonts and merozoites, resolve the spatial proteome and assign locations to previously unknown proteins, but what was next?
2/7