Veronica Finazzi
@veronicafin.bsky.social
PhD student at Helmholtz Munich (Scialdone Lab)
Reposted by Veronica Finazzi
🧠🔬 New research from our Testa Group sheds light on Gabriele-de Vries Syndrome: using advanced stem cell models, the team reveals how YY1 mutations disrupt brain development, offering new insights into potential treatments
In Molecular Psychiatry
humantechnopole.it/en/news/shed...
In Molecular Psychiatry
humantechnopole.it/en/news/shed...
Shedding light on the molecular mechanisms of Gabriele-de Vries Syndrome - Human Technopole
Using advanced stem cell models, Human Technopole researchers show how mutations in the YY1 gene cause widespread dysregulation of genes crucial for brain development in multiple cell types, leading t...
humantechnopole.it
March 12, 2025 at 2:37 PM
🧠🔬 New research from our Testa Group sheds light on Gabriele-de Vries Syndrome: using advanced stem cell models, the team reveals how YY1 mutations disrupt brain development, offering new insights into potential treatments
In Molecular Psychiatry
humantechnopole.it/en/news/shed...
In Molecular Psychiatry
humantechnopole.it/en/news/shed...
Reposted by Veronica Finazzi
I'm proud to share that our modeling of #YY1 haploinsufficiency has just been published! www.nature.com/articles/s41... Using #organoids and #neurons we discovered that YY1 mutations affect the cross-talk between cells and also cause a non-cell autonomous phenotype in a cell-type specific manner.
Article Metrics - YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs | Molecular Psychiatry
www.nature.com
February 24, 2025 at 4:04 PM
I'm proud to share that our modeling of #YY1 haploinsufficiency has just been published! www.nature.com/articles/s41... Using #organoids and #neurons we discovered that YY1 mutations affect the cross-talk between cells and also cause a non-cell autonomous phenotype in a cell-type specific manner.