Jan-Willem Veening
@veeninglab.com
Professor and director at the Department of Fundamental Microbiology, University of Lausanne, https://veeninglab.com/. Interested in antibiotic resistance, bacterial cell biology, host-microbe interactions.
Reposted by Jan-Willem Veening
First the link to the preprint: www.biorxiv.org/content/10.1...
Systematic mapping of bacteriophage gene essentiality with HIDEN‑SEQ
The constant arms race of bacteriophages and their bacterial hosts has inspired major breakthroughs in biotechnology and shaped phages as fierce predators with great clinical potential to fight multid...
www.biorxiv.org
November 20, 2025 at 6:52 PM
First the link to the preprint: www.biorxiv.org/content/10.1...
Also see the accompanying paper from Carol Gross' lab that used a similar approach for Bacillus subtilis: www.cell.com/cell-systems...
Comprehensive genetic interaction analysis of the Bacillus subtilis envelope using double-CRISPRi
Koo et al. apply genome-scale double-CRISPRi to map cell envelope gene interactions
in Bacillus subtilis, revealing >1,000 genetic interactions and uncovering gene networks
in envelope biogenesis and ...
www.cell.com
October 4, 2025 at 8:48 AM
Also see the accompanying paper from Carol Gross' lab that used a similar approach for Bacillus subtilis: www.cell.com/cell-systems...
Now online: www.cell.com/cell-systems...
Dual CRISPRi-seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle
Dénéréaz et al. introduce dual CRISPRi-seq, a broadly applicable method to chart gene-gene
interactions across whole genomes. Applying it to the pathogen Streptococcus pneumoniae,
they uncovered over ...
www.cell.com
October 4, 2025 at 8:42 AM
Now online: www.cell.com/cell-systems...
Reposted by Jan-Willem Veening
It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in therapy. What would need to change? Researcher Alexander Harms explains.
ethz.ch/en/news-and-...
ethz.ch/en/news-and-...
“Treatment with bacteriophages can combat antibiotic-resistant infections, but Swiss patients lack access”
It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in th...
ethz.ch
September 26, 2025 at 6:42 AM
It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in therapy. What would need to change? Researcher Alexander Harms explains.
ethz.ch/en/news-and-...
ethz.ch/en/news-and-...