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The core-resistance genes could serve as potential markers to detect resistant cells during algal blooms. A better understanding of algal resistance mechanisms is key to unraveling the host-virus arms race in the ocean and bloom dynamics. 🌊 >>

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Advancements in single-cell technologies are opening new frontiers in marine microbiology, helping us answer some of the most fundamental questions in marine microbiology and providing a holistic view of microbial life in the ocean.

>> The expression of these resistance-related genes was found to be shared among various resistant strains and included genes with domains linked to innate immune responses that are conserved across bacteria, plants and mammals. 🦠🌊

Cathepsin X mutants in distant algae had increased resilience to oxidative stress. Our findings shed light on the origin of programmed cell death in unicellular organisms and their strategies to cope with environmental fluctuations. 3/3

Using cell-to-cell heterogeneity in response to oxidative stress, we discovered genes linked to either cell death or stress resilience in diatoms. Among the hits we detected was Cathepsin X, a cysteine protease conserved from humans to algae and widely expressed in the oceans. 2/3 >>