Pierre Vanderhaeghen
@vanderhaeghenp2.bsky.social
Neuroscientist at VIB KULeuven
Reposted by Pierre Vanderhaeghen
Turns out eye colour (mainly a result of iris pigmentation) is yet another complex trait, now demystified by genomic advances. DNA variants in two neighbouring genes (HERC2 & OCA2) explain much of the blue-brown variation, but analyses of ~193k people in 2021 revealed another 50 genetic loci. 👇 7/n
Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color
A GWAS including 192,986 European and 1636 Asian participants identifies 50 novel discrete associations with eye color.
www.science.org
May 2, 2025 at 3:15 PM
Turns out eye colour (mainly a result of iris pigmentation) is yet another complex trait, now demystified by genomic advances. DNA variants in two neighbouring genes (HERC2 & OCA2) explain much of the blue-brown variation, but analyses of ~193k people in 2021 revealed another 50 genetic loci. 👇 7/n