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Study: Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS

Published: November 07, 2025

www.cell.com/cell-reports...

You can find our COVID-related updates at pmc19.com/data

In 1-3 weeks, we expect to see a significant departure from the lull.

We also post updates routinely on IG, Twitter, TikTok, and occasionally LinkedIn. 🙏

ME/CFS, as well as anomalous clotting processes.
@resiapretorius.bsky.social @dbkell.bsky.social

Cardiovascular and haematological pathology in #ME/CFS: A role for viruses (2023)

and these abnormalities do not appear to be influenced by deconditioning. Rather, these cardiac abnormalities may result from dysfunction in the (autonomic) nervous system. Plenty of recently published studies are demonstrating significant platelet hyperactivity and endothelial dysfunction in

Wyller from Norway is a big BpS peddler too.

technological. It requires investing in the caregiving workforce, strengthening publicly owned systems for both medical and social care, expanding the welfare state to combat growing inequality, and creating conditions for clinicians to care for patients as people, not data.

society itself.

Perhaps the most dangerous assumption behind the rise of AI in medicine is that its current trajectory and private ownership structure is inevitable. When we refuse this narrative of inevitability, we can finally recognize that the real alternative to our present is political, not

www.medscape.com/viewarticle/...

Clinical Implications

For those with comorbid CFS/ME and chronic pain, interventions targeting the management of multiple symptoms may be particularly important.

months for me to recover… As you leave work today, please remember us. We will be confined to our homes and our beds. We will be living in hope that you will take action to end the needless discrimination and suffering that people #ME/CFS have endured.”

– Tracey Collins, Living with ME/CFS #pwME

and economic burden of disease, … future-proofing… over the next 25 years the likelihood is a 50% chance of another such pandemic [like COVID-19]. We need to future-proof against the inevitable resulting high burden of post-pandemic viral and bacterial diseases.”

– Professor
@cgatist.bsky.social

Research – Building on discoveries like DecodeME, a National ME/CFS Research Strategy is essential to guide investment and unlock diagnostic and treatment breakthroughs.
“There are three reasons why ME deserves a national [research] strategy: a high prevalence…, a huge and substantial health, social