USC INI
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USC's Stevens Neuroimaging and Informatics Institute (INI) applies innovative imaging and information technologies to studying the brain. We share our data and resources with thousands of collaborators around the world. Home of Lab of Neuro Imaging (LONI).
Dr. Kay Jann used fMRI and tau PET to show that Alzheimer’s patients have less complex brain activity at rest—linked to higher tau buildup and poorer cognition. Measuring brain signal complexity may aid early detection and tracking of AD.
Learn more: bit.ly/48tSbwe
bit.ly/4ndzRfB
Learn more: bit.ly/48tSbwe
bit.ly/4ndzRfB
ADNI fMRI and tau PET data measuring complexity of brain activity changes in Alzheimer's Disease
Dr. Kay Jann and his team used functional MRI and tau PET to examine how brain activity complexity changes in Alzheimer’s disease (AD) and its relationship to tau protein accumulation, a key marker of AD. We found that individuals with AD exhibit less complex brain activity during rest. This reduction in complexity was associated with higher levels of tau protein and poorer cognition. These links were seen in both typical and genetic forms of AD. Measuring brain signal complexity could help detect AD earlier and monitor its progression, even before major symptoms develop. Learn more: http://bit.ly/48tSbwe
bit.ly
September 21, 2025 at 12:19 PM
Dr. Kay Jann used fMRI and tau PET to show that Alzheimer’s patients have less complex brain activity at rest—linked to higher tau buildup and poorer cognition. Measuring brain signal complexity may aid early detection and tracking of AD.
Learn more: bit.ly/48tSbwe
bit.ly/4ndzRfB
Learn more: bit.ly/48tSbwe
bit.ly/4ndzRfB