Jianhan Chen
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umassmdlab.bsky.social
Jianhan Chen
@umassmdlab.bsky.social
Professor at UMass Amherst; computational biophysics: intrinsically disordered proteins, ion channels, protein nanopores, biomolecular condensates, multi-scale RNA and protein modeling, enhanced sampling
Excited to share our new coarse grained model of dynamic RNA for phase separation simulations. The model is still evolving and any feedback is welcomed!

www.biorxiv.org/content/10.1...
An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+
RNAs are major drivers of phase separation in the formation of biomolecular condensates. Recent studies suggest that RNAs can also undergo protein-free phase separation in the presence of divalent ion...
www.biorxiv.org
December 3, 2024 at 3:13 AM