Twist Bioscience
@twistbioscience.com
Synthetic DNA for Health & Sustainability
“Targeted long-read methylation analysis using hybridization capture suitable for clinical specimens” uses Twist Methylation Products + Custom panel for long read methylation:
Targeted long-read methylation analysis using hybridization capture suitable for clinical specimens
To detect precise DNA methylation patterns in long-read DNA sequencing analysis, an efficient target enrichment method is needed. In this study, we es…
www.sciencedirect.com
November 11, 2025 at 2:22 PM
“Targeted long-read methylation analysis using hybridization capture suitable for clinical specimens” uses Twist Methylation Products + Custom panel for long read methylation:
From @leopoldparts.bsky.social and team now in preprint, “Generating long deletions across the genome with pooled paired prime editing screens” presents Twist Multiplexed Gene Fragments in a functional genomics screen, building paired pegRNA libraries.
Generating long deletions across the genome with pooled paired prime editing screens
Engineered deletions are a powerful probe for studying genome architecture, function, and regulation. Yet, the lack of effective methods to create them in large numbers and at multi-kilobase scale has...
www.biorxiv.org
November 11, 2025 at 2:22 PM
From @leopoldparts.bsky.social and team now in preprint, “Generating long deletions across the genome with pooled paired prime editing screens” presents Twist Multiplexed Gene Fragments in a functional genomics screen, building paired pegRNA libraries.
Breakthrough in lung cancer monitoring from James RM Black, Charles Swanton, and team, in Cell: “Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction.”
Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction
Longitudinal ultrasensitive ctDNA detection improves disease stratification accuracy,
demonstrates clinical utility for adjuvant therapy, and reveals insights into characteristic
features of relapse i...
www.cell.com
November 11, 2025 at 2:21 PM
Breakthrough in lung cancer monitoring from James RM Black, Charles Swanton, and team, in Cell: “Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction.”
From the David Baker lab: “Atomically accurate de novo design of antibodies with RFdiffusion.”
Huge thanks for the shoutout in the acknowledgement section: “Twist Bioscience for access to their 400-bp oligo synthesis, which was invaluable for the high-throughput VHH experiments.”
Huge thanks for the shoutout in the acknowledgement section: “Twist Bioscience for access to their 400-bp oligo synthesis, which was invaluable for the high-throughput VHH experiments.”
Atomically accurate de novo design of antibodies with RFdiffusion - Nature
The combination of computational design, laboratory-based screening and biophysical validation enables the de novo generation of variable heavy-chain antibody fragments and antibodies that precis...
www.nature.com
November 11, 2025 at 2:21 PM
From the David Baker lab: “Atomically accurate de novo design of antibodies with RFdiffusion.”
Huge thanks for the shoutout in the acknowledgement section: “Twist Bioscience for access to their 400-bp oligo synthesis, which was invaluable for the high-throughput VHH experiments.”
Huge thanks for the shoutout in the acknowledgement section: “Twist Bioscience for access to their 400-bp oligo synthesis, which was invaluable for the high-throughput VHH experiments.”
Read the blog: www.microsoft.com/en-us/resear...
Watch the podcast: www.microsoft.com/en-us/resear...
Dive into the paper: www.microsoft.com/en-us/resear...
TL;DR: youtu.be/NtwlQdruK-0
@twistbioscience.com, @msftresearch.bsky.social
Watch the podcast: www.microsoft.com/en-us/resear...
Dive into the paper: www.microsoft.com/en-us/resear...
TL;DR: youtu.be/NtwlQdruK-0
@twistbioscience.com, @msftresearch.bsky.social
The Paraphrase Project: Designing defense for an era of synthetic biology
Microsoft researchers reveal a confidential research effort that explored how open-source AI tools could be used to bypass biosecurity checks—and helped create fixes now influencing global standards.
www.microsoft.com
November 10, 2025 at 3:49 PM
Read the blog: www.microsoft.com/en-us/resear...
Watch the podcast: www.microsoft.com/en-us/resear...
Dive into the paper: www.microsoft.com/en-us/resear...
TL;DR: youtu.be/NtwlQdruK-0
@twistbioscience.com, @msftresearch.bsky.social
Watch the podcast: www.microsoft.com/en-us/resear...
Dive into the paper: www.microsoft.com/en-us/resear...
TL;DR: youtu.be/NtwlQdruK-0
@twistbioscience.com, @msftresearch.bsky.social
Congratulations on your preprint! 🧬
November 6, 2025 at 1:26 PM
Congratulations on your preprint! 🧬
Reposted by Twist Bioscience
Then we scaled up. Using improved long oligo synthesis (@twistbioscience.com), we encoded both pegRNAs in a single construct, enabling true pooled paired prime editing. We designed 10,471 deletions across 149 genes using the PE7 system from Britt Adamson's lab.
November 5, 2025 at 2:17 PM
Then we scaled up. Using improved long oligo synthesis (@twistbioscience.com), we encoded both pegRNAs in a single construct, enabling true pooled paired prime editing. We designed 10,471 deletions across 149 genes using the PE7 system from Britt Adamson's lab.
Read more about the tournament here:
www.businesswire.com/news/home/20...
Register here: alignbio.org/get-involved...
www.businesswire.com/news/home/20...
Register here: alignbio.org/get-involved...
www.businesswire.com
October 27, 2025 at 1:19 PM
Read more about the tournament here:
www.businesswire.com/news/home/20...
Register here: alignbio.org/get-involved...
www.businesswire.com/news/home/20...
Register here: alignbio.org/get-involved...
➡️ If your team received free DNA from Twist, stop by Booth X03 — we’ve got a special thank-you token waiting just for you!
October 23, 2025 at 1:22 PM
➡️ If your team received free DNA from Twist, stop by Booth X03 — we’ve got a special thank-you token waiting just for you!