Tsvi Tlusty
Tsvi Tlusty
@tsvit.bsky.social
Scientist
#Enzymes = viscoelastic catalytic machines
whose mechano-chemical specifications are encoded in the gene.

QY Tang has now written a lucid news & views piece on this idea in doi.org/10.1038/s415...
The mechanics of protein sweet spots - Nature Physics
Proteins rely on dynamic flexibility to function as life’s molecular machines. Now, artificial intelligence predictions and mechanics experiments reveal how mutations at specific protein sites modulat...
doi.org
March 31, 2025 at 3:30 AM
#Enzymes = viscoelastic catalytic machines whose mechano-chemical specifications are encoded in the gene.

You can read more on how to measure and model all this at rdcu.be/efug8.
March 28, 2025 at 12:00 PM
Reposted by Tsvi Tlusty
"Motivated by seventeenth-century insights into this infinity, this paper proposes a language to discuss life as an infinite double cascade of machines making machines. The two cascades meet at the critical point of 10^3 s in time and 1 micron in length.."
www.pnas.org/doi/10.1073/...
🧪 #EvoBio
February 14, 2025 at 2:16 PM
Thank you ‪@andrejpaleo! Since many people could not access "Life sets off a cascade of machines" on PNAS, I uploaded a preprint at hal.science/hal-04968880...
March 6, 2025 at 4:14 AM