@hophenrimondor.bsky.social @ap-hp.bsky.social

- Hybrid GFR, defined as the mean between CT-mGFR and eGFRcr-cys would be even more accurate.
These results open up new perspectives, particularly for patients with kidney cancer or urothelial carcinoma.

Measuring GFR using CT urography performed as part of routine care is possible not only in healthy individuals, but also in patients with CKD.
In this study, we demonstrate that:
- GFR measured by CT is more accurate than GFR estimated from creatinine, cystatin C, or both (eGFRcr-cys).

Congratulations to Michael Moryoussef for this first original study, to Antoine Morel, the statistician in chief for this work ;-), and to all the co-authors.

In addition to diabetes and male gender, we identified myosteatosis and low muscle mass as predisposing factors. Visceral and subcutaneous fat mass were not determinants of the low ratio.

We show that a low eGFR ratio is associated with the occurrence of major cardiovascular events, whether using CKD-EPI or EKFC equations.

The originality of this study also lies in our attempt to identify the determinants of such a low ratio by including body composition data in the analyses.

Very pleased to share this publication from @hophenrimondor.bsky.social .
A low eGFRcys/eGFRcr ratio is increasingly recognized as a risk factor for morbidity and mortality, including CV events.
However, there was little or no data available on kidney transplantation.

Bravo Antoine pour cet édito avec deux co auteurs prestigieux !

While frailty is often difficult to identify, myosteatosis is easy to detect on the basis of unenhanced abdominal CT scans performed as part of routine care.

We previously showed that myosteatosis was associated with mortality after kidney transplantation (10.1002/jcsm.12853).
It is therefore likely that myosteatosis is associated with frailty, in addition to cardiovascular risk.