@tronstadlab.bsky.social
5/5-The multiscale protein patterns map a pathophysiology composed of interrelated elements that are likely to play roles in ME/CFS.
June 2, 2025 at 4:09 PM
5/5-The multiscale protein patterns map a pathophysiology composed of interrelated elements that are likely to play roles in ME/CFS.
4/5-Focused studies of secreted proteins (the secretome) supported intensified regulatory interactions related to immune activity, inflammation, vasculature, and metabolism.
June 2, 2025 at 4:09 PM
4/5-Focused studies of secreted proteins (the secretome) supported intensified regulatory interactions related to immune activity, inflammation, vasculature, and metabolism.
3/5-The widespread decrease of intracellular proteins in the blood (especially from skeletal muscle) may have different explanations - muscle mass, cell/tissue turnover, tissue perfusion, and more.
June 2, 2025 at 4:09 PM
3/5-The widespread decrease of intracellular proteins in the blood (especially from skeletal muscle) may have different explanations - muscle mass, cell/tissue turnover, tissue perfusion, and more.
2/5-Distinct patterns of tissue- and process-specific changes were seen, including broad increase in secreted proteins, effects on metabolic regulators and changes in immune cell-specific signatures - with a specific reduction in neutrophil-associated proteins.
June 2, 2025 at 4:09 PM
2/5-Distinct patterns of tissue- and process-specific changes were seen, including broad increase in secreted proteins, effects on metabolic regulators and changes in immune cell-specific signatures - with a specific reduction in neutrophil-associated proteins.