Tim Julian
trj2.bsky.social
Tim Julian
@trj2.bsky.social
scientist at Eawag
Check out the website here: genspectrum.org/swiss-wastew.... And follow our work tracking virus loads in #RSV here: wise.ethz.ch. We're still in the middle of an #RSV wave now, but it looks like the peak may be behind us.
Swiss wastewater - RSV
GenSpectrum is an interactive dashboard to query and analyze pathogen sequences, currently available for Influenza H5N1, RSV, SARS-CoV-2 and the West Nile virus.
genspectrum.org
February 27, 2025 at 9:54 AM
So now back to our work sequencing #RSV, available from #Genspectrum website: We can track genomic changes in virus regions targeted by #Nirsevimab and the vaccines, to detect, within the population, whether or not the virus mutates in ways that may confer resistance to our available treatments.
February 27, 2025 at 9:53 AM
But the good news is, in #Switzerland, we have monoclonal antibody Nirsevimab for infants to reduce risks of severe disease, or as a prophylaxis to prevent infections in at-risk infants. We also have two vaccines against #RSV approved for the elderly: www.bag.admin.ch/bag/en/home/...
Respiratory syncytial virus (RSV)
RS viruses cause colds and bronchiolitis during the winter half-year. They often lead to hospitalisation. Now there are possibilities for prevention, including the antibody Nirsevimab for newborns and...
www.bag.admin.ch
February 27, 2025 at 9:51 AM
«Wir haben momentan keine Reserve mehr an freien Betten mit pflegerischer Betreuung.» Christoph Berger said at the time, as reported in @20min.ch www.20min.ch/story/wegen-...
RSV: Wegen diesem Virus sind die Kinderspitäler überfüllt
Wegen des sogenannten Respiratorischen Synzytial-Virus (RSV) müssen immer mehr Kleinkinder und Säuglinge in der Schweiz im Spital behandelt werden.
www.20min.ch
February 27, 2025 at 9:48 AM
Another number that's important is #hospitalizations. #CDC estimates 130-260k hospitalizations in the #US. These are infections severe enough to require a hospital bed, which means that bed is not available for other illnesses. In 2022-23, #Switzerland, a huge RSV wave impacted hospitals...
February 27, 2025 at 9:47 AM
#RSV is a common #respiratory virus. We've probably all had it at some point in our life. For most of us, its a nuisance* But for some people, including #children and the elderly, its deadly. #CDC reports an estimated 7k-16k deaths due to RSV this season alone. www.cdc.gov/rsv/php/surv...
February 27, 2025 at 9:42 AM
The mutation impacts the digital PCR efficiency, resulting in an underestimate of the concentration (for N1). As a consequence, we now monitor the ratio as part of our weekly QA/QC. We observe some fluctuation from week to week, but the ratio has returned back to 1.
January 17, 2025 at 1:09 PM
We observed a decoupling in the ratio consistent with a mutation in the forward primer region, which increased and then decreased throughout 2023: cov-spectrum.org/explore/Swit...
covSPECTRUM
covSPECTRUM is an interactive platform aiming to help scientists investigate and identify variants of SARS-CoV-2.
cov-spectrum.org
January 17, 2025 at 1:07 PM
Yes, we have data from mid-2022; we're working on updating our database to include older data, it should be up in a week or two.
January 17, 2025 at 1:05 PM