Translational Research Immunology Group
@triglab-oxford.bsky.social
We are interested in translational aspects of immunological research in transplant, cancer and autoimmunity. Based at University of Oxford.
We're excited to share our latest research, published in
@NatureComms
Engineering "off the shelf" Tregs for use in transplantation. A great collaboration with our colleagues in Berlin. rdcu.be/eKZRk
@NatureComms
Engineering "off the shelf" Tregs for use in transplantation. A great collaboration with our colleagues in Berlin. rdcu.be/eKZRk
HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model
Nature Communications - Adoptive regulatory T cell (Treg) therapy holds promise for the treatment of a range of immunopathological conditions. Here the authors explore the HLA engineering of...
rdcu.be
October 14, 2025 at 3:54 PM
We're excited to share our latest research, published in
@NatureComms
Engineering "off the shelf" Tregs for use in transplantation. A great collaboration with our colleagues in Berlin. rdcu.be/eKZRk
@NatureComms
Engineering "off the shelf" Tregs for use in transplantation. A great collaboration with our colleagues in Berlin. rdcu.be/eKZRk
Listen to Helen and QY discuss the what you can expect from the recent Sam Strober workshop meeting report, out now in @transplantation.bsky.social
tts.org/podcast2
tts.org/podcast2
May 29, 2025 at 2:07 PM
Listen to Helen and QY discuss the what you can expect from the recent Sam Strober workshop meeting report, out now in @transplantation.bsky.social
tts.org/podcast2
tts.org/podcast2
Expanding Human Breg for Cellular Therapy in Transplantation: Time for Translation journals.lww.com/transplantjo...
Nice work team!
@ndsurgicalsci.bsky.social @transplantation.bsky.social
Nice work team!
@ndsurgicalsci.bsky.social @transplantation.bsky.social
May 24, 2025 at 7:15 AM
Expanding Human Breg for Cellular Therapy in Transplantation: Time for Translation journals.lww.com/transplantjo...
Nice work team!
@ndsurgicalsci.bsky.social @transplantation.bsky.social
Nice work team!
@ndsurgicalsci.bsky.social @transplantation.bsky.social
We are happy to share this news 👏
New Professor of Transplantation appointed www.nds.ox.ac.uk/news/new-pro...
New Professor of Transplantation appointed www.nds.ox.ac.uk/news/new-pro...
New Professor of Transplantation appointed
Fadi Issa has been appointed as our new Professor of Transplantation at the Nuffield Department of Surgical Sciences (NDS), following an internationally competitive appointment process. He will take u...
www.nds.ox.ac.uk
April 23, 2025 at 2:10 PM
We are happy to share this news 👏
New Professor of Transplantation appointed www.nds.ox.ac.uk/news/new-pro...
New Professor of Transplantation appointed www.nds.ox.ac.uk/news/new-pro...
Our team includes plastic surgeons with an interest in melanoma management. The latest on this:
Tumor-infiltrating lymphocyte scoring improves progression risk prediction in stage II melanoma: A retrospective cohort study - Journal of the American Academy of Dermatology www.jaad.org/article/S019...
Tumor-infiltrating lymphocyte scoring improves progression risk prediction in stage II melanoma: A retrospective cohort study - Journal of the American Academy of Dermatology www.jaad.org/article/S019...
Tumor-infiltrating lymphocyte scoring improves progression risk prediction in stage II melanoma: A retrospective cohort study
The American Joint Committee on Cancer eighth edition substaging might be suboptimal
for predicting melanoma progression. Using it to select stage II patients for adjuvant
immunotherapy risks overtrea...
www.jaad.org
April 16, 2025 at 4:24 PM
Our team includes plastic surgeons with an interest in melanoma management. The latest on this:
Tumor-infiltrating lymphocyte scoring improves progression risk prediction in stage II melanoma: A retrospective cohort study - Journal of the American Academy of Dermatology www.jaad.org/article/S019...
Tumor-infiltrating lymphocyte scoring improves progression risk prediction in stage II melanoma: A retrospective cohort study - Journal of the American Academy of Dermatology www.jaad.org/article/S019...
We enjoy collaborating --> here we look at ways to edit Tregs
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer: Molecular Therapy www.cell.com/molecular-th...
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer: Molecular Therapy www.cell.com/molecular-th...
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer
Wagner and colleagues demonstrate that non-viral CRISPR-Cas12a knock-in of antigen-binding
domains into CD3ε generates dual-responsive CD3ε-TRuC Tregs that can signal via the
TCR and the transgenic bi...
www.cell.com
April 16, 2025 at 4:20 PM
We enjoy collaborating --> here we look at ways to edit Tregs
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer: Molecular Therapy www.cell.com/molecular-th...
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer: Molecular Therapy www.cell.com/molecular-th...
Opening our account here with a recap of our publications this year...
This paper reviews the current state of play in the field of tolerance (and of course of favourite Tregs)
Meeting Report: The Sixth International Sam Strober... : Transplantation journals.lww.com/transplantjo...
This paper reviews the current state of play in the field of tolerance (and of course of favourite Tregs)
Meeting Report: The Sixth International Sam Strober... : Transplantation journals.lww.com/transplantjo...
Meeting Report: The Sixth International Sam Strober... : Transplantation
An abstract is unavailable.
journals.lww.com
April 16, 2025 at 4:16 PM
Opening our account here with a recap of our publications this year...
This paper reviews the current state of play in the field of tolerance (and of course of favourite Tregs)
Meeting Report: The Sixth International Sam Strober... : Transplantation journals.lww.com/transplantjo...
This paper reviews the current state of play in the field of tolerance (and of course of favourite Tregs)
Meeting Report: The Sixth International Sam Strober... : Transplantation journals.lww.com/transplantjo...