Travis Lee
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tralee-sci.bsky.social
Travis Lee
@tralee-sci.bsky.social
Post doc in the Ecker lab @ The Salk Institute. PhD in the Bailey-Serres lab @ UCR. Posts include papers I'm reading and things that I 3D print

@TrALEE_Sci on Twitter
We hope that this 'initial draft' of a spatially-resolved cell atlas of the Arabidopsis lifecycle will enable further biological discovery and function as a framework for future focused studies. 6/end
August 19, 2025 at 9:17 AM
We also took a deep dive investigating cell states within the compact yet complex hypocotyl apical hook where we found that our paired spatial + single-cell datasets were key for identifying novel cellular states at the intersection of development and hormonal regulation. 4/n
August 19, 2025 at 9:17 AM
We found novel and subtle phenotypes visible to the naked eye in mutants of genes with combined cell type and developmental expression specificity.

These results highlight that our dataset can guide novel discovery by knowing when and where a gene is natively expressed. 3/n
August 19, 2025 at 9:17 AM
With our approach of paired single-nucleus and spatial transcriptomics to diverse Arabidopsis organs, we identified and spatially validated cases of both conserved and divergent markers of coocell types and cell states along the Arabidopsis lifecycle. 2/n
August 19, 2025 at 9:17 AM
Thrilled to have our spatial single-cell atlas of the Arabidopsis lifecycle in @NaturePlants. Turns out that its easy to make nice images when spatial expression of 1,000 genes is available! 1/n
@natanellae.bsky.social @tatsuyanobori.bsky.social @joeecker.bsky.social

www.nature.com/articles/s41...
August 19, 2025 at 9:17 AM
We hope that this 'initial draft' of a spatially-resolved cell atlas of the Arabidopsis lifecycle will enable further biological discovery and function as a framework for future focused studies. 6/endph
August 19, 2025 at 9:03 AM
We also took a deep dive investigating cell states within the compact yet complex hypocotyl apical hook where we found that our paired spatial + single-cell datasets were key for identifying novel cellular states at the intersection of development and hormonal regulation. 4/n
August 19, 2025 at 9:03 AM
We found novel and subtle phenotypes visible to the naked eye in mutants of genes with combined cell type and developmental expression specificity.

These results highlight that our dataset can guide novel discovery by knowing when and where a gene is natively expressed. 3/n
August 19, 2025 at 9:03 AM
With our paired application of single-nucleus and spatial transcriptomics to diverse Arabidopsis organs, we identified and spatially validated cases of both conserved and divergent markers of cell types and cell states along the Arabidopsis lifecycle. 2/n
August 19, 2025 at 9:03 AM
Graphical abstract of the year award goes to

www.sciencedirect.com/science/arti...
June 12, 2025 at 10:23 PM
Can't beat the view leaving from lab
August 11, 2023 at 4:10 AM