@tomsextonlab.bsky.social
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Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics
Gene promoters and enhancers share the same constrained mobilities during transcription, opposing cohesin-mediated loop extrusion.
science.org
Out now in
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin
The perfect addition to our Christmas tree: an ES cell and a cancer cell, knitted by the super talented @cathieerb
December 20, 2024 at 7:04 AM
The perfect addition to our Christmas tree: an ES cell and a cancer cell, knitted by the super talented @cathieerb
From 2023: out now in @plosbiology.org
👇 TLDR: Transcription CAN directly remodel TADs... in specific contexts. Big congrats to Sanjay and @yousra_zouari
who spearheaded the project, and @djost_physbiol
+Hossein
👇 TLDR: Transcription CAN directly remodel TADs... in specific contexts. Big congrats to Sanjay and @yousra_zouari
who spearheaded the project, and @djost_physbiol
+Hossein
December 16, 2024 at 8:41 AM
From 2023: out now in @plosbiology.org
👇 TLDR: Transcription CAN directly remodel TADs... in specific contexts. Big congrats to Sanjay and @yousra_zouari
who spearheaded the project, and @djost_physbiol
+Hossein
👇 TLDR: Transcription CAN directly remodel TADs... in specific contexts. Big congrats to Sanjay and @yousra_zouari
who spearheaded the project, and @djost_physbiol
+Hossein
We've now joined BlueSky - we'll try and catch up with all the Twitter/X expats asap
December 16, 2024 at 8:39 AM
We've now joined BlueSky - we'll try and catch up with all the Twitter/X expats asap
Out now in
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin
Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics
Gene promoters and enhancers share the same constrained mobilities during transcription, opposing cohesin-mediated loop extrusion.
science.org
December 16, 2024 at 8:35 AM
Out now in
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin
@ScienceAdvances
👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatin