Tomás M. Tessi
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tomastessi.bsky.social
Tomás M. Tessi
@tomastessi.bsky.social
Plant Molecular Biologist. Ex-CONICET 🇦🇷 #Humboldtian PD at @COSHeidelberg 🇩🇪. Love P🌵L🌱A🌿N☘️T🌴S🌾. Proteomics, RNA, roots, development. Father of 2
And finally, a brief piece reviewing and discussing how AZGs fit into the CK signaling scenario in #BiochemSocTrans. For more details, feel free to DM!

VoR: doi.org/10.1042/BST2...
AAM: drive.google.com/file/d/12occ...
@PPPublishing
AZGs: a new family of cytokinin transporters
Cytokinins (CKs) are phytohormones structurally similar to purines that play important roles in various aspects of plant physiology and development. The local and long-distance distribution of CKs is ...
doi.org
January 28, 2025 at 9:38 AM
In summary, AZGs are not only important for CK transport and its signalling, but they represent hubs for auxin:CK crosstalk at different levels.

And personally it's great to see how the work of so many years is validated by a different approach on the other side of the globe🌍
January 28, 2025 at 9:38 AM
Then, was the time for AZG1. Despite a high level similarity to AZG2, AZG1 has a different mechanism to transport CK. But, what makes AZG1 specially interesting is that its presence is important for the stability of the auxin transporter PIN1.

nph.onlinelibrary.wiley.com/doi/10.1111/...
AZG1 is a cytokinin transporter that interacts with auxin transporter PIN1 and regulates the root stress response
An environmentally responsive root system is crucial for plant growth and crop yield, especially in suboptimal soil conditions. This responsiveness enables the plant to exploit regions of high nutri...
nph.onlinelibrary.wiley.com
January 28, 2025 at 9:38 AM
First, we described that AZG2 can take up CK with high affinity. AZG2 expression is tightly regulated (by auxins 🧐), being present only in a few cells surrounding lateral root primordia. In these cells, AZG2 activity is important for CK signaling.

nph.onlinelibrary.wiley.com/doi/10.1111/...
Arabidopsis AZG2 transports cytokinins in vivo and regulates lateral root emergence
Cytokinin and auxin are key regulators of plant growth and development. During the last decade transport mechanisms have turned out to be the key for the control of local and long-distance hormone...
nph.onlinelibrary.wiley.com
January 28, 2025 at 9:38 AM