Alejandra Tomas
@tomaslab-imperial.bsky.social
Professor & Head of Section of Cell Biology and Functional Genomics, MDR Department, Imperial College London. Subcellular signalling organisation of the glucagon receptor family.
https://www.imperial.ac.uk/people/a.tomas-catala
https://www.imperial.ac.uk/people/a.tomas-catala
I’m delighted to share that I have been promoted to Professor of Cell Biology at Imperial College London. I am deeply grateful to those who have supported me along the way, through the many ups and downs that led to this point.
August 31, 2025 at 3:08 PM
I’m delighted to share that I have been promoted to Professor of Cell Biology at Imperial College London. I am deeply grateful to those who have supported me along the way, through the many ups and downs that led to this point.
And a new paper from our group now published in DOM on a novel dual GLP-1R/GIPR agonist with improved action in vivo
doi.org/10.1111/dom....
doi.org/10.1111/dom....
August 20, 2025 at 3:11 PM
And a new paper from our group now published in DOM on a novel dual GLP-1R/GIPR agonist with improved action in vivo
doi.org/10.1111/dom....
doi.org/10.1111/dom....
Our newest study looking at the impact of missense GIPR variants in BMI versus glycemia, receptor stability, and pancreatic islet function.
www.medrxiv.org/content/10.1...
A collaboration of Imperial College with Eli Lilly and University of Cambridge.
www.medrxiv.org/content/10.1...
A collaboration of Imperial College with Eli Lilly and University of Cambridge.
Glycaemic and bodyweight effects of GIPR coding variation reflect differences in both surface expression and intrinsic functional impairment
The glucose-dependent insulinotropic polypeptide receptor (GIPR) is the target of several approved and investigational drugs for type 2 diabetes and obesity. Missense coding variation in GIPR could co...
www.medrxiv.org
August 20, 2025 at 3:10 PM
Our newest study looking at the impact of missense GIPR variants in BMI versus glycemia, receptor stability, and pancreatic islet function.
www.medrxiv.org/content/10.1...
A collaboration of Imperial College with Eli Lilly and University of Cambridge.
www.medrxiv.org/content/10.1...
A collaboration of Imperial College with Eli Lilly and University of Cambridge.
Still time to apply to this Lectureship position in our Section. Deadline 25th March.
Are you interested in developing a research programme in cell biology of diabetes? Do you work in pancreatic islets and/or other metabolically relevant cells? We have a Lectureship post opening in our Section @imperialcollegeldn.bsky.social
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
March 9, 2025 at 2:24 PM
Still time to apply to this Lectureship position in our Section. Deadline 25th March.
Congratulations to Liliane ElEid who successfully passed her PhD viva yesterday! Here are some pictures of the post-viva celebrations. Many thanks to Prof David Hodson @daveyboyhod.bsky.social and Dr Bryn Owen for assessing her thesis and to David for his visit and Seminar.
March 8, 2025 at 3:04 PM
Congratulations to Liliane ElEid who successfully passed her PhD viva yesterday! Here are some pictures of the post-viva celebrations. Many thanks to Prof David Hodson @daveyboyhod.bsky.social and Dr Bryn Owen for assessing her thesis and to David for his visit and Seminar.
Our newly revised manuscript on ER-mitochondria membrane contact site-localised GLP-1R signalling hub now out in bioRxiv: www.biorxiv.org/content/10.1...
GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function
Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RAs) ameliorate mitochondrial health by increasing mitochondrial turnover in metabolically relevant tissues. Mitochondrial adaptation under met...
www.biorxiv.org
February 15, 2025 at 3:40 PM
Our newly revised manuscript on ER-mitochondria membrane contact site-localised GLP-1R signalling hub now out in bioRxiv: www.biorxiv.org/content/10.1...
Are you interested in developing a research programme in cell biology of diabetes? Do you work in pancreatic islets and/or other metabolically relevant cells? We have a Lectureship post opening in our Section @imperialcollegeldn.bsky.social
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
February 15, 2025 at 10:00 AM
Are you interested in developing a research programme in cell biology of diabetes? Do you work in pancreatic islets and/or other metabolically relevant cells? We have a Lectureship post opening in our Section @imperialcollegeldn.bsky.social
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Apply by 25th March:
www.imperial.ac.uk/jobs/search-...
Our newest preprint about a new GLP-1R/GIPR dual agonist:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Binding Kinetics, Bias, Receptor Internalization and Effects on Insulin Secretion in vitro and in vivo of a Novel GLP-1R/GIPR Dual Agonist, HISHS-2001
The use of incretin analogues has emerged in recent years as an effective approach to achieve both enhanced insulin secretion and weight loss in type 2 diabetes (T2D) patients. Agonists which bind and...
www.biorxiv.org
January 17, 2025 at 8:17 PM
Our newest preprint about a new GLP-1R/GIPR dual agonist:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Last few days to apply for a postdoc position in my lab
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
January 6, 2025 at 11:05 PM
Last few days to apply for a postdoc position in my lab
Our collaboration with the talented Sarah Rouse now out in bioRxiv:
"Human class B1 GPCR modulation by plasma membrane lipids"
www.biorxiv.org/content/10.1...
"Human class B1 GPCR modulation by plasma membrane lipids"
www.biorxiv.org/content/10.1...
www.biorxiv.org
December 22, 2024 at 11:34 AM
Our collaboration with the talented Sarah Rouse now out in bioRxiv:
"Human class B1 GPCR modulation by plasma membrane lipids"
www.biorxiv.org/content/10.1...
"Human class B1 GPCR modulation by plasma membrane lipids"
www.biorxiv.org/content/10.1...
Still time to apply to this position! Application open until 15th Jan 2025.
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
December 20, 2024 at 11:13 AM
Still time to apply to this position! Application open until 15th Jan 2025.
PhD Studentship available in the lab of Dr Paras Anand at Imperial, in collaboration with me:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Deciphering the metabolic regulation of inflammasome activation at Imperial College London on FindAPhD.com
PhD Project - Deciphering the metabolic regulation of inflammasome activation at Imperial College London, listed on FindAPhD.com
www.findaphd.com
December 13, 2024 at 9:08 AM
PhD Studentship available in the lab of Dr Paras Anand at Imperial, in collaboration with me:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
December 8, 2024 at 4:07 PM
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...