Alexey Tolchinsky
tolchinsky.bsky.social
Alexey Tolchinsky
@tolchinsky.bsky.social
Clinical psychologist and researcher investigating anxiety disorders, Acute PTSD, dissociations, OCD, Affective Neuroscience, neuropsychoanalysis, application of nonlinear dynamical systems to psychology

https://montgomerycountypsychologist.com
November 4, 2025 at 4:12 PM
Citation: "Higher baseline bodyweight was associated with larger antidepressant-induced increases in systolic blood pressure, ALT, and AST, and higher baseline age was associated with larger antidepressant-induced increases in glucose."
November 4, 2025 at 4:12 PM
Pillinger, T., Arumuham, A., McCutcheon, R. A., D’Ambrosio, E., Basdanis, G., Branco, M., ... & Cipriani, A. (2025). The effects of antidepressants on cardiometabolic and other physiological parameters: a systematic review and network meta-analysis. The Lancet.
November 4, 2025 at 4:12 PM
November 1, 2025 at 11:55 AM
Then, strictly speaking, we can' have "observer-independent" explanations. Causality in Fields' view is assumed, not deduced or measured and "control" does not change that.
November 1, 2025 at 11:55 AM
"cause" as in A causes B, observer, control, "why" - these are all classical, not quantum concepts. Chris goes further to suggest that "everything in classical physics is observer-dependent," which means that nothing is entirely "objective."
November 1, 2025 at 11:55 AM
Bio-chemical models of psychiatric conditions, e.g. a chemical imbalance story of depression is not an explanation, it's an example of narrative fallacy.

www.psychologytoday.com/us/blog/embr...

#explanation
#scientific
#method
#prediction
#narrativefallacy
Narrative Fallacy in Clinical Psychology and Psychiatry
Narrative fallacy is a ubiquitous challenge affecting psychotherapy and psychiatry. We can talk about it.
www.psychologytoday.com
October 31, 2025 at 1:35 PM
Psychoanalytic models, which we call case formulations - none of them are explanations in a scientific sense. They are descriptions, as psychoanalysts like to say "ways of thinking about something." Sometimes they are hypotheses, and nearly always these hypotheses are not falsifiable.
October 31, 2025 at 1:35 PM
(With perhaps, one exception - Acute PTSD, where an exposure of an individual with a certain predisposition to a severe enough traumatic episode results in the onset.)
October 31, 2025 at 1:35 PM
Mark Solms agrees that our psychiatric system of classification and diagnosis is not an etiological system, be in DSM or ICD

www.therapyroute.com/article/the-...
www.therapyroute.com
October 31, 2025 at 1:35 PM
Even a combination of describe, classify and predict do not "explain. By "explain" she means being able to answer the "Why" rigorously and reliably and, more importantly, being able to control the target causally.

www.youtube.com/watch?v=laj2...
Explanation in Biology: Principles and Pragmatics by Lauren N. Ross
YouTube video by Michael Levin's Academic Content
www.youtube.com
October 31, 2025 at 1:35 PM