It's very long, and quite dense in places, so here are my favourite hosts discussing it.

Beware, this is a half hour NotebookLM AI generated conversation. I've not had a chance to check it got all the details right...

notebooklm.google.com/notebook/9bf...

It's also because it helps to down regulate glucagon production by the same pathways that in a healthy system, increase insulin response.

Add in GABA (another key missing endocrine component) and you really start to see the effects.