Timothy Gottschalk
timothygottschalk.bsky.social
Timothy Gottschalk
@timothygottschalk.bsky.social
Postdoc, Cell Death and Inflammatory Signalling, Hudson Institute | All posts are my own
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Hi bluesky, just wanted to share our most recent paper from the
@katelawlorlab.bsky.social showing distinct roles for #necroptosis effectors RIPK3 (+ Caspase-8) that drives inflammation, and MLKL which regulates lipid handling in obesity-induced #MAFLD. www.life-science-alliance.org/content/8/1/...
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
Cell death frequently occurs in the pathogenesis of obesity and metabolic dysfunction–associated fatty liver disease (MAFLD). However, the exact contribution of core cell death machinery to disease ma...
www.life-science-alliance.org
If you have a minute why not take a look at this study I am very proud to be a part of out today in Allergy, demonstrating how CD53 drives immune cell infiltration and inflammation but controls mucus production in allergic airway asthma-like disease. doi.org/10.1111/all....
Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation
Click on the article title to read more.
doi.org
December 9, 2024 at 11:49 PM
Hi bluesky, just wanted to share our most recent paper from the
@katelawlorlab.bsky.social showing distinct roles for #necroptosis effectors RIPK3 (+ Caspase-8) that drives inflammation, and MLKL which regulates lipid handling in obesity-induced #MAFLD. www.life-science-alliance.org/content/8/1/...
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
Cell death frequently occurs in the pathogenesis of obesity and metabolic dysfunction–associated fatty liver disease (MAFLD). However, the exact contribution of core cell death machinery to disease ma...
www.life-science-alliance.org
December 5, 2024 at 10:53 PM