Timothy Fuqua 🏳🌈
@timothyfuqua.bsky.social
Incoming postdoc in Claudia Bank’s lab. Promoters, emergence, fitness landscapes, dogs 🐶 and triathlon 🏊 🚲 🏃. He/him 🏳🌈.
timothyfuqua.com
timothyfuqua.com
I’m looking forward to these next steps, and if you’re in Bern (or Stockholm), please get in touch!
October 30, 2025 at 5:57 PM
I’m looking forward to these next steps, and if you’re in Bern (or Stockholm), please get in touch!
…Starting in January, I’ll be working as a postdoc with Claudia Bank @cbank.bsky.social at the University of Bern, and collaborating with RIke Stelkens @stelkens.bsky.social on some exciting experimental evolution in yeast…
October 30, 2025 at 5:57 PM
…Starting in January, I’ll be working as a postdoc with Claudia Bank @cbank.bsky.social at the University of Bern, and collaborating with RIke Stelkens @stelkens.bsky.social on some exciting experimental evolution in yeast…
Reposted by Timothy Fuqua 🏳🌈
...(Hot take) Because there is a correlation between promoter strength and robustness, I don't think we can rule out the counterintuitive possibility that some promoters are actually selected for their robustness, and not necessarily their strength.
October 21, 2025 at 8:02 AM
...(Hot take) Because there is a correlation between promoter strength and robustness, I don't think we can rule out the counterintuitive possibility that some promoters are actually selected for their robustness, and not necessarily their strength.
...(Hot take) Because there is a correlation between promoter strength and robustness, I don't think we can rule out the counterintuitive possibility that some promoters are actually selected for their robustness, and not necessarily their strength.
October 21, 2025 at 8:02 AM
...(Hot take) Because there is a correlation between promoter strength and robustness, I don't think we can rule out the counterintuitive possibility that some promoters are actually selected for their robustness, and not necessarily their strength.
...that in general, robustness increases with promoter strength. However, differences in spacer lengths, -10/-35 box composition, and overlapping -10/-35 boxes overlap can further increase robustness...
October 21, 2025 at 8:02 AM
...that in general, robustness increases with promoter strength. However, differences in spacer lengths, -10/-35 box composition, and overlapping -10/-35 boxes overlap can further increase robustness...
...we use a thermodynamic promoter model (elifesciences.org/articles/64543) to identify different sequence features associated with promoter mutational robustness. We find...
Predicting bacterial promoter function and evolution from random sequences
An inferred mechanistic model that connects sequence (genotype) to function (constitutive gene expression phenotype) for any random sequence in Escherichia coli reveals the structure of constitutive p...
elifesciences.org
October 21, 2025 at 8:02 AM
...we use a thermodynamic promoter model (elifesciences.org/articles/64543) to identify different sequence features associated with promoter mutational robustness. We find...