@timothychase.bsky.social
Interests include quantum computation, climatology, evolutionary biology, photography, hiking, and the Mandelbrot set.
I've heard that viruses that get infected by virophages find virophages nothing to sneeze at though.
November 13, 2025 at 9:55 PM
I've heard that viruses that get infected by virophages find virophages nothing to sneeze at though.
He seemed to be falling apart at the end. I can sympathize.
November 13, 2025 at 8:46 AM
He seemed to be falling apart at the end. I can sympathize.
Not meaning to imply that he was working for Russia, but the term seems appropriate. Though I suspect the intelligence agencies of several countries (including Russia) found him an asset.
November 13, 2025 at 8:39 AM
Not meaning to imply that he was working for Russia, but the term seems appropriate. Though I suspect the intelligence agencies of several countries (including Russia) found him an asset.
uninsightful, humorous quips. As far as I know, the intellectuals weren't participants in the illegal activity and didn't know about it, but some tech bros were a different matter, having the wealth and politicians the power that made kompromat worthwhile.
November 13, 2025 at 8:39 AM
uninsightful, humorous quips. As far as I know, the intellectuals weren't participants in the illegal activity and didn't know about it, but some tech bros were a different matter, having the wealth and politicians the power that made kompromat worthwhile.
Epstein presumably used intellectuals (e.g., physicists including Hawking) as a means of burnishing his reputation and even funded conferences. Earlier on he presumably actually took an interest in what was being said and asked intelligent questions. Later he would join in only for...
November 13, 2025 at 8:39 AM
Epstein presumably used intellectuals (e.g., physicists including Hawking) as a means of burnishing his reputation and even funded conferences. Earlier on he presumably actually took an interest in what was being said and asked intelligent questions. Later he would join in only for...
there are also the bits of good news, such as the fact that Germany is offering those displaced by politics a new home among their institutions.
At this point I will call it a night. Take care.
At this point I will call it a night. Take care.
November 13, 2025 at 8:21 AM
there are also the bits of good news, such as the fact that Germany is offering those displaced by politics a new home among their institutions.
At this point I will call it a night. Take care.
At this point I will call it a night. Take care.
seems unlikely that others will be able to pick up all the slack. Moreover, there are the developments and studies that are likely to be left by the wayside and the scientists who, suddenly cut loose from their institutions, will find it difficult to pick up the pieces of their lives.
But then...
But then...
November 13, 2025 at 8:21 AM
seems unlikely that others will be able to pick up all the slack. Moreover, there are the developments and studies that are likely to be left by the wayside and the scientists who, suddenly cut loose from their institutions, will find it difficult to pick up the pieces of their lives.
But then...
But then...
PS You mention how the United States is losing its leadership position, particularly in medical research. I think things are much worse than that. While many countries are partners, it is my understanding that an outsized proportion of research was being funded by the United States and it...
November 13, 2025 at 8:21 AM
PS You mention how the United States is losing its leadership position, particularly in medical research. I think things are much worse than that. While many countries are partners, it is my understanding that an outsized proportion of research was being funded by the United States and it...
virulent and is no longer something any of us can afford.
November 13, 2025 at 7:33 AM
virulent and is no longer something any of us can afford.
took advantage of the opportunity they provided.
Anyway, I hope that we are able to get past the politicized anti-science that has achieved such a grip on our societies soon. The science denial is bad enough, but the mixture of money and politics (particularly in climate) has become especially...
Anyway, I hope that we are able to get past the politicized anti-science that has achieved such a grip on our societies soon. The science denial is bad enough, but the mixture of money and politics (particularly in climate) has become especially...
November 13, 2025 at 7:33 AM
took advantage of the opportunity they provided.
Anyway, I hope that we are able to get past the politicized anti-science that has achieved such a grip on our societies soon. The science denial is bad enough, but the mixture of money and politics (particularly in climate) has become especially...
Anyway, I hope that we are able to get past the politicized anti-science that has achieved such a grip on our societies soon. The science denial is bad enough, but the mixture of money and politics (particularly in climate) has become especially...
infected given your travels and the number of people you came in contact with. I remember that back in February of 2020 a pharma company held a large meeting, bringing in people from Europe, regarding the opportunity that the epidemic was affording them of developing new medicine and SARS-CoV-2...
November 13, 2025 at 7:33 AM
infected given your travels and the number of people you came in contact with. I remember that back in February of 2020 a pharma company held a large meeting, bringing in people from Europe, regarding the opportunity that the epidemic was affording them of developing new medicine and SARS-CoV-2...
received some bad news about the condition of our cat, which as it turned out was incorrect.) I was infected twice more and my wife only once again. So I can sympathize with what you went through. At a certain level it seems almost surprising that you made it as far as you did without getting...
November 13, 2025 at 7:33 AM
received some bad news about the condition of our cat, which as it turned out was incorrect.) I was infected twice more and my wife only once again. So I can sympathize with what you went through. At a certain level it seems almost surprising that you made it as far as you did without getting...
to a commercial N95-ish I trusted and along with my wife managed to keep from getting infected for over two years. When virus levels were presumably low across the nation we dropped a mask for perhaps 15 seconds in an environment that was poorly ventilated. (We were at the vet and had just...
November 13, 2025 at 7:33 AM
to a commercial N95-ish I trusted and along with my wife managed to keep from getting infected for over two years. When virus levels were presumably low across the nation we dropped a mask for perhaps 15 seconds in an environment that was poorly ventilated. (We were at the vet and had just...
out and no longer being able to maintain the stalemate. Alternatively it may be the case that a particular mutation resulted in a major advantage.
Incidentally, I took up wearing masks everywhere (except outdoors) constructing my own high filtration masks while I had to then switching...
Incidentally, I took up wearing masks everywhere (except outdoors) constructing my own high filtration masks while I had to then switching...
November 13, 2025 at 7:33 AM
out and no longer being able to maintain the stalemate. Alternatively it may be the case that a particular mutation resulted in a major advantage.
Incidentally, I took up wearing masks everywhere (except outdoors) constructing my own high filtration masks while I had to then switching...
Incidentally, I took up wearing masks everywhere (except outdoors) constructing my own high filtration masks while I had to then switching...
new major variants.
I am curious though: is the well defined phase transition, where one linear trend is suddenly replaced by another, the rule? Do we have an understanding of the mechanism behind it? I can imagine it being the result of the patient's immune system simply giving...
I am curious though: is the well defined phase transition, where one linear trend is suddenly replaced by another, the rule? Do we have an understanding of the mechanism behind it? I can imagine it being the result of the patient's immune system simply giving...
November 13, 2025 at 7:33 AM
new major variants.
I am curious though: is the well defined phase transition, where one linear trend is suddenly replaced by another, the rule? Do we have an understanding of the mechanism behind it? I can imagine it being the result of the patient's immune system simply giving...
I am curious though: is the well defined phase transition, where one linear trend is suddenly replaced by another, the rule? Do we have an understanding of the mechanism behind it? I can imagine it being the result of the patient's immune system simply giving...
and phase transition. In such cases the total number of mutations acquired by the dominant strain was on the order of a hundred, roughly the same scale as those of a new major variant.
At this point I believe it is widely accepted that individuals such as these were the likely source of the...
At this point I believe it is widely accepted that individuals such as these were the likely source of the...
November 13, 2025 at 7:33 AM
and phase transition. In such cases the total number of mutations acquired by the dominant strain was on the order of a hundred, roughly the same scale as those of a new major variant.
At this point I believe it is widely accepted that individuals such as these were the likely source of the...
At this point I believe it is widely accepted that individuals such as these were the likely source of the...
in South Africa (a country that played an oversized role in the study of SARS-CoV-2 with cutting-edge virology as I remember) who was HIV positive and on antivirals. At some point she lost access to the antivirals and her compromised immune system exhibited the same sort of "jailbreak phenomena"...
November 13, 2025 at 7:33 AM
in South Africa (a country that played an oversized role in the study of SARS-CoV-2 with cutting-edge virology as I remember) who was HIV positive and on antivirals. At some point she lost access to the antivirals and her compromised immune system exhibited the same sort of "jailbreak phenomena"...
being replaced by another. As I remember, this particular individual was not the source of a new major variant that managed to break out and sweep the globe, but he demonstrated the sort of mechanism by which such variants might very well originate. Another somewhat similar case was a woman...
November 13, 2025 at 7:33 AM
being replaced by another. As I remember, this particular individual was not the source of a new major variant that managed to break out and sweep the globe, but he demonstrated the sort of mechanism by which such variants might very well originate. Another somewhat similar case was a woman...
several months it was as if his infection went though some sort of phase transition. There was more variation in the viral population as a whole and the dominant strain kept getting replaced, acquiring not two mutations each week but more like ten. The graph I saw clearly showed one linear trend...
November 13, 2025 at 7:33 AM
several months it was as if his infection went though some sort of phase transition. There was more variation in the viral population as a whole and the dominant strain kept getting replaced, acquiring not two mutations each week but more like ten. The graph I saw clearly showed one linear trend...
out of nowhere. I remember hearing of the case of an English patient with a compromised immune system. I believe he was on chemo at the time. He was chronicly infected by SARS-CoV-2 at the time, maintaining a fairly stable viral population with a relatively stable degree of variation. But after...
November 13, 2025 at 7:33 AM
out of nowhere. I remember hearing of the case of an English patient with a compromised immune system. I believe he was on chemo at the time. He was chronicly infected by SARS-CoV-2 at the time, maintaining a fairly stable viral population with a relatively stable degree of variation. But after...
Thank you for sharing this interview. I found it wide-ranging and highly informative and greatly appreciate having the opportunity to see the pandemic through the eyes of someone who saw so much. In the interview you touch on puzzle of the origin of major variants which seemed to come...
November 13, 2025 at 7:33 AM
Thank you for sharing this interview. I found it wide-ranging and highly informative and greatly appreciate having the opportunity to see the pandemic through the eyes of someone who saw so much. In the interview you touch on puzzle of the origin of major variants which seemed to come...
Seriously? Given what I have seen of Steve Kornacki's analysis of elections on MSNBC in the past it can be pretty hard to come up from behind, and given how far ahead Harrell was late last week I am surprised. Not terribly surprised, but surprised nevertheless.
November 12, 2025 at 7:00 AM
Seriously? Given what I have seen of Steve Kornacki's analysis of elections on MSNBC in the past it can be pretty hard to come up from behind, and given how far ahead Harrell was late last week I am surprised. Not terribly surprised, but surprised nevertheless.
reduction in the strength of the Atlantic Meridional Overturning Circulation (implying ocean stratification) and the poleward expansion of the subtropics and consequent reduction in atmospheric circulation and the ocean circulation that is driven by it.
November 12, 2025 at 6:43 AM
reduction in the strength of the Atlantic Meridional Overturning Circulation (implying ocean stratification) and the poleward expansion of the subtropics and consequent reduction in atmospheric circulation and the ocean circulation that is driven by it.
reason why colder ocean waters appear so green and are better able to support life than the clearer waters of the tropics. The story itself points to ocean stratification, which obviously will also reduce the ability for gases to become suspended in water at depth. Additionally one has the...
November 12, 2025 at 6:43 AM
reason why colder ocean waters appear so green and are better able to support life than the clearer waters of the tropics. The story itself points to ocean stratification, which obviously will also reduce the ability for gases to become suspended in water at depth. Additionally one has the...