Tim Katz
@thuxemsao2024.bsky.social
Reposted by Tim Katz
Mature Human Bone Marrow Plasma Cells Secrete More IgG than Early-Minted Blood Antibody-Secreting Cells #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-6585905/latest
https://www.researchsquare.com/article/rs-6585905/latest
June 27, 2025 at 4:00 PM
Mature Human Bone Marrow Plasma Cells Secrete More IgG than Early-Minted Blood Antibody-Secreting Cells #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-6585905/latest
https://www.researchsquare.com/article/rs-6585905/latest
Reposted by Tim Katz
Without Vaccines and/or Infections inducing Long Lasting Plasma cells - if we are not vaccinated - and relying on short lasting plasma cells with no mitigations - we are on the way to extinction - via disability from Long Covid already over 25% of Population.
#1: www.nature.com/articles/s41...
#1: www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
March 26, 2025 at 10:35 AM
Reposted by Tim Katz
Sorry Ryan - I am posting something to spread what NIH and HHS is trying to do to evidence and our lives:
#1:
bsky.app/profile/670r...
#1:
bsky.app/profile/670r...
Without Vaccines and/or Infections inducing Long Lasting Plasma cells - if we are not vaccinated - and relying on short lasting plasma cells with no mitigations - we are on the way to extinction - via disability from Long Covid already over 25% of Population.
#1: www.nature.com/articles/s41...
#1: www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
March 26, 2025 at 2:49 PM
Sorry Ryan - I am posting something to spread what NIH and HHS is trying to do to evidence and our lives:
#1:
bsky.app/profile/670r...
#1:
bsky.app/profile/670r...
Reposted by Tim Katz
And humans do not have a way to induce long lasting plasma cells to respond to with infection or present vaccines against SARS CoV2 and they ended mitigations after the vaccines - which provide protection for ~ 4 months:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
March 27, 2025 at 10:33 AM
And humans do not have a way to induce long lasting plasma cells to respond to with infection or present vaccines against SARS CoV2 and they ended mitigations after the vaccines - which provide protection for ~ 4 months:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tim Katz
Without Vaccines and/or Infections inducing Long Lasting Plasma cells - if we are not vaccinated - and relying on short lasting plasma cells with no mitigations - we are on the way to extinction - via disability from Long Covid already over 25% of Population.
#1: www.nature.com/articles/s41...
#1: www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
March 25, 2025 at 10:02 PM
Without Vaccines and/or Infections inducing Long Lasting Plasma cells - if we are not vaccinated - and relying on short lasting plasma cells with no mitigations - we are on the way to extinction - via disability from Long Covid already over 25% of Population.
#1: www.nature.com/articles/s41...
#1: www.nature.com/articles/s41...
Reposted by Tim Katz
In case there are questions about the bone marrow thing.
pubmed.ncbi.nlm.nih.gov/39333316/
pubmed.ncbi.nlm.nih.gov/39333316/
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - PubMed
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are effective at protecting from severe disease, but the protective antibodies wane rapidly even though SARS-CoV-2-specific p...
pubmed.ncbi.nlm.nih.gov
January 7, 2025 at 12:18 AM
In case there are questions about the bone marrow thing.
pubmed.ncbi.nlm.nih.gov/39333316/
pubmed.ncbi.nlm.nih.gov/39333316/
Reposted by Tim Katz
It is not just immune evasive viral variants but something more fundamental about this famSARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination (or infection): (E)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
January 17, 2025 at 9:41 PM
It is not just immune evasive viral variants but something more fundamental about this famSARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination (or infection): (E)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tim Katz
Reposted by Tim Katz
Reposted by Tim Katz
I have Long Covid and moved to BC to escape the UCP. For my latest booster I crossed the border to the US and paid out of pocket for Novavax, mostly after reading this... www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
January 27, 2025 at 7:46 AM
I have Long Covid and moved to BC to escape the UCP. For my latest booster I crossed the border to the US and paid out of pocket for Novavax, mostly after reading this... www.nature.com/articles/s41...
Reposted by Tim Katz
pubmed.ncbi.nlm.nih.gov/39333316/
In all, our studies suggest that rapid waning of SARS-CoV-2-specific serum antibodies could be accounted for by the absence of BM LLPCs after these mRNA vaccines. (same with infection)
In all, our studies suggest that rapid waning of SARS-CoV-2-specific serum antibodies could be accounted for by the absence of BM LLPCs after these mRNA vaccines. (same with infection)
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - PubMed
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are effective at protecting from severe disease, but the protective antibodies wane rapidly even though SARS-CoV-2-specific p...
pubmed.ncbi.nlm.nih.gov
January 30, 2025 at 7:16 PM
pubmed.ncbi.nlm.nih.gov/39333316/
In all, our studies suggest that rapid waning of SARS-CoV-2-specific serum antibodies could be accounted for by the absence of BM LLPCs after these mRNA vaccines. (same with infection)
In all, our studies suggest that rapid waning of SARS-CoV-2-specific serum antibodies could be accounted for by the absence of BM LLPCs after these mRNA vaccines. (same with infection)
Reposted by Tim Katz
With no Long Lasting Plasma cells against SARS CoV2 either by infection or vaccination - anybody against other mitigations - are either disinformation peddlers or minimizers- no other way!
Mitigations + boosters in that order- booster complement mitigations.
pubmed.ncbi.nlm.nih.gov/39333316/
Mitigations + boosters in that order- booster complement mitigations.
pubmed.ncbi.nlm.nih.gov/39333316/
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - PubMed
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are effective at protecting from severe disease, but the protective antibodies wane rapidly even though SARS-CoV-2-specific p...
pubmed.ncbi.nlm.nih.gov
January 31, 2025 at 3:45 PM
With no Long Lasting Plasma cells against SARS CoV2 either by infection or vaccination - anybody against other mitigations - are either disinformation peddlers or minimizers- no other way!
Mitigations + boosters in that order- booster complement mitigations.
pubmed.ncbi.nlm.nih.gov/39333316/
Mitigations + boosters in that order- booster complement mitigations.
pubmed.ncbi.nlm.nih.gov/39333316/
Reposted by Tim Katz
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination (and/or infection):
Without mitigation unless we get a different effective platform- as a species we are cooked!
www.nature.com/articles/s41...
Without mitigation unless we get a different effective platform- as a species we are cooked!
www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
February 11, 2025 at 5:42 PM
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination (and/or infection):
Without mitigation unless we get a different effective platform- as a species we are cooked!
www.nature.com/articles/s41...
Without mitigation unless we get a different effective platform- as a species we are cooked!
www.nature.com/articles/s41...
Reposted by Tim Katz
or infection for about ~ 4months.
We have evidence since 2022 and now published: that there is no induction of Long Lasting Plasma Cells (pDCs, T cells and NK Cells are ineffective against this virus)
(B):
www.nature.com/articles/s41...
We have evidence since 2022 and now published: that there is no induction of Long Lasting Plasma Cells (pDCs, T cells and NK Cells are ineffective against this virus)
(B):
www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
February 11, 2025 at 10:23 PM
or infection for about ~ 4months.
We have evidence since 2022 and now published: that there is no induction of Long Lasting Plasma Cells (pDCs, T cells and NK Cells are ineffective against this virus)
(B):
www.nature.com/articles/s41...
We have evidence since 2022 and now published: that there is no induction of Long Lasting Plasma Cells (pDCs, T cells and NK Cells are ineffective against this virus)
(B):
www.nature.com/articles/s41...
Reposted by Tim Katz
#3 : There is no long lasting immunity either with vaccine and/or infection:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
February 14, 2025 at 12:14 AM
#3 : There is no long lasting immunity either with vaccine and/or infection:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tim Katz
www.nature.com/articles/s41...
Either with infection or vaccine.
Will he fix ventilation, effective N95 masks and UVC lighting- or sending children for 200 days a school year - 8 hours a day - for 5 years to continue
Either with infection or vaccine.
Will he fix ventilation, effective N95 masks and UVC lighting- or sending children for 200 days a school year - 8 hours a day - for 5 years to continue
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow speci...
www.nature.com
February 14, 2025 at 8:17 PM
www.nature.com/articles/s41...
Either with infection or vaccine.
Will he fix ventilation, effective N95 masks and UVC lighting- or sending children for 200 days a school year - 8 hours a day - for 5 years to continue
Either with infection or vaccine.
Will he fix ventilation, effective N95 masks and UVC lighting- or sending children for 200 days a school year - 8 hours a day - for 5 years to continue
Reposted by Tim Katz
An explanation for the observed short-lived humoral memory against SARS Cov2 and COVID 19 vaccines
February 17, 2025 at 5:51 PM
An explanation for the observed short-lived humoral memory against SARS Cov2 and COVID 19 vaccines
Reposted by Tim Katz
Reposted by Tim Katz
• Vaccination: MRNA covid vaccines do not induce long-lived plasma cells.
https://www.nature.com/articles/s41591-024-03278-y
https://www.nature.com/articles/s41591-024-03278-y
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination - Nature Medicine
The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in the bone marrow specific for the virus.
www.nature.com
December 12, 2024 at 5:52 PM
• Vaccination: MRNA covid vaccines do not induce long-lived plasma cells.
https://www.nature.com/articles/s41591-024-03278-y
https://www.nature.com/articles/s41591-024-03278-y
Reposted by Tim Katz
And I'm saying the short-term antibody measure of efficacy isn't a good measure of vaccine efficacy. Some studies:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.sciencedirect.com/science/arti...
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.sciencedirect.com/science/arti...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.sciencedirect.com/science/arti...
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.sciencedirect.com/science/arti...
December 19, 2024 at 9:07 PM
And I'm saying the short-term antibody measure of efficacy isn't a good measure of vaccine efficacy. Some studies:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.sciencedirect.com/science/arti...
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.sciencedirect.com/science/arti...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.sciencedirect.com/science/arti...
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.sciencedirect.com/science/arti...
Reposted by Tim Katz
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
https://www.nature.com/articles/s41591-024-03278-y
t.co
December 13, 2024 at 1:47 AM
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
https://www.nature.com/articles/s41591-024-03278-y
t.co
December 13, 2024 at 1:47 AM
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
Reposted by Tim Katz
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
https://www.nature.com/articles/s41591-024-03278-y
t.co
December 2, 2024 at 12:23 PM
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP
https://www.nature.com/articles/s41591-024-03278-y
t.co
December 2, 2024 at 12:23 PM
Such a beautiful study! Yes, its beauty chiefly lies at its simplicity &/yet (real-life) relevancy. Congratulations @NatureMedicine! t.co/sBRUfIv2pP