The Thistle and the Unicorn
thistleandunicorn.bsky.social
The Thistle and the Unicorn
@thistleandunicorn.bsky.social
Covering the Companies and Academic Research Groups that make up the Scottish Life Science Sector
Reposted by The Thistle and the Unicorn
On TV tonight - edin.ac/3EHc7Q2 - our Race Against Dementia lab have broken new ground. Using live brain tissue, they have shown for the 1st time how a toxic form a protein linked to #Alzheimer’s can stick to and damage synapses. Next steps: developing drugs to combat this!
April 30, 2025 at 4:04 PM
A very interesting read on the history and successes the DDU at the University of Dundee
Good morning sky pals!

Here's a good read for your morning coffee:
Navigating the Landscape of Academic #DrugDiscovery: An 18-Year Journey, written by our very own Dr Beatriz Baragana & Dr Laura Cleghorn for @acs.org

pubs.acs.org/doi/full/10....
Navigating the Landscape of Academic Drug Discovery: An 18-Year Journey
pubs.acs.org
April 11, 2025 at 11:09 PM
Reposted by The Thistle and the Unicorn
🚀 University of Glasgow launches the Innovation Cluster Development Fund, offering financial support to researchers and academic staff aiming to develop spin-out ventures or commercialise innovative ideas

📍 @uofglasgow.bsky.social
👇 Learn more

glasgowcityofscienceandinnovation.com/new-universi...
New University Of Glasgow Fund To Boost Innovation Clusters | Glasgow City Of Science & Innovation
The University of Glasgow has launched a new fund to help support its researchers and academic staff who want to start a new venture or spin-out company.
glasgowcityofscienceandinnovation.com
January 14, 2025 at 10:31 AM
An interesting paper from Stevens et al. at @unistrathclyde.bsky.social and GSK, expanding their work in high-throughput PROTAC synthesis and D2B screening.

Features a neat exploitation of base-mediated chemoselectivity to explore two separate vectors from a RIPK2 binder.

doi.org/10.1039/D4MD...
Expanding the reaction toolbox for nanoscale direct-to-biology PROTAC synthesis and biological evaluation
High-throughput chemistry (HTC) and direct-to-biology (D2B) platforms allow for plate-based compound synthesis and biological evaluation of crude mixtures in cellular assays. The rise of these workflo...
doi.org
January 13, 2025 at 12:53 PM
The results of a Phase II clinical trial (MATCH) by Edinburgh Biotech Resolution Therapeutics @edinuni-irr.bsky.social have been published in @naturemedicine.bsky.social.

They are now enrolling for a larger Phase II trial (EMERALD) in the UK and Spain.

www.nature.com/articles/s41...
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial - Nature Medicine
Results from the phase 2 MATCH01 clinical trial of autologous monocyte-derived macrophage therapy for liver cirrhosis revealed no liver-related severe adverse events or deaths in the treatment group.
www.nature.com
January 12, 2025 at 9:14 PM
This month will see the Scottish Cross Sector Hub hold their launch event at the Golden Jubilee National Hospital in Glasgow.

The Hub aims to bring together stakeholders from across sectors to spur health and life science innovation.

Register here: www.tickettailor.com/events/nhsre...
Register for the event – Scottish Cross-Sector Hub Launch Event – Golden Jubilee National Hospital
The ability to work and collaborate successfully across sectors is hugely beneficial in health and life science research and in...
www.tickettailor.com
January 12, 2025 at 4:47 PM