Kim Huggler
@thebiokimist.bsky.social
Reposted by Kim Huggler
excited to share our latest work now online
@natmetabolism.nature.com, led by
@kyle-flickinger.bsky.social, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
@natmetabolism.nature.com, led by
@kyle-flickinger.bsky.social, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
May 2, 2025 at 3:32 PM
excited to share our latest work now online
@natmetabolism.nature.com, led by
@kyle-flickinger.bsky.social, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
@natmetabolism.nature.com, led by
@kyle-flickinger.bsky.social, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
Reposted by Kim Huggler
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!
Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1
February 10, 2025 at 6:40 PM
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!
Reposted by Kim Huggler
a fitting first post to mark the beautiful PhD thesis defense this afternoon from our lab’s very first student! Kim’s courage to join a brand-new lab and her ensuing grit, enthusiasm, and creativity were exceptional! extremely proud of all she has achieved, stay tuned for some of her cool findings!
December 3, 2024 at 10:48 PM
a fitting first post to mark the beautiful PhD thesis defense this afternoon from our lab’s very first student! Kim’s courage to join a brand-new lab and her ensuing grit, enthusiasm, and creativity were exceptional! extremely proud of all she has achieved, stay tuned for some of her cool findings!