Edward Fon
@tedfon.bsky.social
Scientific Director, Montreal Neurological Institute-Hospital, Professor, McGill University
Emma MacDougall’s paper showing the interaction between the two PD genes, LRRK2 and GBA1, in human iPSC microglia is now online can01.safelinks.protection.outlook.com?url=https%3A...
LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli
Variants in the LRRK2 and GBA1 genes are among the most common risk factors associated with Parkinson's disease (PD). Both patients carrying PD-associated variants in GBA1, encoding lysosomal enzyme g...
can01.safelinks.protection.outlook.com
October 12, 2025 at 7:46 PM
Emma MacDougall’s paper showing the interaction between the two PD genes, LRRK2 and GBA1, in human iPSC microglia is now online can01.safelinks.protection.outlook.com?url=https%3A...
Zaid Al-Azzawi’s paper showing the importance of the alpha-Synuclein purification method on the consistency of the Seed Amplification Assay (SAA) is now online. www.biorxiv.org/cgi/content/...
α-Synuclein purification significantly impacts seed amplification assay performance and consistency
α-Synuclein seed amplification assays are a promising diagnostic tool for synucleinopathies such as Parkinson disease and multiple system atrophy. Standardized conditions are required to ensure a high...
www.biorxiv.org
May 14, 2025 at 9:37 PM
Zaid Al-Azzawi’s paper showing the importance of the alpha-Synuclein purification method on the consistency of the Seed Amplification Assay (SAA) is now online. www.biorxiv.org/cgi/content/...
Ghislaine Deyab’s paper showing that midbrain organoids from patients with Parkinson’s disease exhibit hallmarks of network activity abnormalities seen in vivo is now out on biorxiv. www.biorxiv.org/cgi/content/...
Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity
Human midbrain organoids (hMOs) show promise as a patient-derived model for the study of Parkinson's disease (PD). Yet, much remains unknown about how accurately hMOs recapitulate key features of PD i...
www.biorxiv.org
April 24, 2025 at 8:26 PM
Ghislaine Deyab’s paper showing that midbrain organoids from patients with Parkinson’s disease exhibit hallmarks of network activity abnormalities seen in vivo is now out on biorxiv. www.biorxiv.org/cgi/content/...
Just got around to closing my X account!
February 25, 2025 at 7:04 PM
Just got around to closing my X account!
Reposted by Edward Fon
The Quebec government has awarded $1.6M to three McGill researchers to support projects advancing genomics, imaging, and manufacturing. These initiatives will foster collaborations and deliver significant benefits to Quebec and beyond.
➡️ mcgill.ca/x/wr8
➡️ mcgill.ca/x/wr8
December 17, 2024 at 8:57 PM
The Quebec government has awarded $1.6M to three McGill researchers to support projects advancing genomics, imaging, and manufacturing. These initiatives will foster collaborations and deliver significant benefits to Quebec and beyond.
➡️ mcgill.ca/x/wr8
➡️ mcgill.ca/x/wr8
Reposted by Edward Fon
A number of colleges, including Harvard, USC and Cornell, are advising their international students to return to campus before President-elect Donald Trump is inaugurated on Jan. 20. nyti.ms/41qkzft
December 13, 2024 at 1:05 AM
A number of colleges, including Harvard, USC and Cornell, are advising their international students to return to campus before President-elect Donald Trump is inaugurated on Jan. 20. nyti.ms/41qkzft
Reposted by Edward Fon
Mood in Montreal today.
December 12, 2024 at 1:00 AM
Mood in Montreal today.
Reposted by Edward Fon
Lab-grown brain cells help uncover new targets for Parkinson’s treatments.
🧠 Researchers at The Neuro have uncovered a new link between the immune system and the development of the disease.
➡️ mcgill.ca/x/wDZ
🧠 Researchers at The Neuro have uncovered a new link between the immune system and the development of the disease.
➡️ mcgill.ca/x/wDZ
November 29, 2024 at 3:54 PM
Lab-grown brain cells help uncover new targets for Parkinson’s treatments.
🧠 Researchers at The Neuro have uncovered a new link between the immune system and the development of the disease.
➡️ mcgill.ca/x/wDZ
🧠 Researchers at The Neuro have uncovered a new link between the immune system and the development of the disease.
➡️ mcgill.ca/x/wDZ
Reposted by Edward Fon
Le Gouvernement du Québec, par l’intermédiaire du CQDM, octroya une subvention de 1,5 million pour la plateforme YCharOS. Ce projet dirigé par les neuroscientifiques @peter-mcpherson.bsky.social et Carl Laflamme, valide des réactifs d’anticorps pour les protéines humaines.
https://buff.ly/3OjmpXD
https://buff.ly/3OjmpXD
Financement de 1,5 million de dollars pour un projet de science ouverte
La plateforme de caractérisation des anticorps YCharOS s’attaque à la « crise de la reproductibilité » dans la recherche Le gouvernement du Québec par l’intermédiaire du CQDM vient d’octroyer une…
buff.ly
November 21, 2024 at 3:00 PM
Le Gouvernement du Québec, par l’intermédiaire du CQDM, octroya une subvention de 1,5 million pour la plateforme YCharOS. Ce projet dirigé par les neuroscientifiques @peter-mcpherson.bsky.social et Carl Laflamme, valide des réactifs d’anticorps pour les protéines humaines.
https://buff.ly/3OjmpXD
https://buff.ly/3OjmpXD
Our new paper on Cathepsin B in Parkinson’s just published rdcu.be/d1sJ2
The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons
rdcu.be
November 28, 2024 at 1:40 AM
Our new paper on Cathepsin B in Parkinson’s just published rdcu.be/d1sJ2