@tamjeed.bsky.social
Reposted
For those who love bacterial replicons, The ultimate review, from our lab, signed by the master of their evolution.
@val-meve.bsky.social www.sciencedirect.com/science/arti...
@val-meve.bsky.social www.sciencedirect.com/science/arti...
Taming wild replicons: evolution and domestication of large extrachromosomal replicons
Bacterial genomes often contain extrachromosomal replicons (ERs), ranging from small, mobile plasmids to large, stably inherited elements, such as meg…
www.sciencedirect.com
August 20, 2025 at 10:28 AM
For those who love bacterial replicons, The ultimate review, from our lab, signed by the master of their evolution.
@val-meve.bsky.social www.sciencedirect.com/science/arti...
@val-meve.bsky.social www.sciencedirect.com/science/arti...
Reposted
Prompt-based bioinformatics: a new interface for multi-omics analysis www.nature.com/articles/s41... read free: rdcu.be/eAnf4
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Prompt-based bioinformatics: a new interface for multi-omics analysis - Nature Reviews Genetics
Prompt-based methods, which involve the careful design of inputs to guide large language model (LLM) outputs, are beginning to reshape bioinformatic analytical workflows. The authors compare prompt-dr...
www.nature.com
August 14, 2025 at 11:51 AM
Prompt-based bioinformatics: a new interface for multi-omics analysis www.nature.com/articles/s41... read free: rdcu.be/eAnf4
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Reposted
(1/7)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)
[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)
[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)
Accelerating Biomolecular Modeling with AtomWorks and RF3
Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...
www.biorxiv.org
August 15, 2025 at 5:17 PM
(1/7)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)
[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)
[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)
Reposted
Absolutely brilliant work by @kaitlynakiernan.bsky.social from my former advisor David Taylor's lab: 25 structures from one kinetics-guided cryo-EM dataset, including the elusive post-cleavage dissociated product state www.nature.com/articles/s41...
Visualization of a multi-turnover Cas9 after product release - Nature Communications
Streptococcus pyogenes Cas9 is perhaps the most widely used CRISPR-Cas enzyme. Here, cryo-EM structures provide insight into the conformational landscape of Cas9 under multi-turnover conditions, sugge...
www.nature.com
July 1, 2025 at 1:40 PM
Absolutely brilliant work by @kaitlynakiernan.bsky.social from my former advisor David Taylor's lab: 25 structures from one kinetics-guided cryo-EM dataset, including the elusive post-cleavage dissociated product state www.nature.com/articles/s41...
Reposted
If I identified the paper you are mentioning correctly, it was later on criticized here share.google/kvHnQjtXCyIJ...
Insufficient evidence for non-neutrality of synonymous mutations - Nature
Nature - Insufficient evidence for non-neutrality of synonymous mutations
share.google
August 8, 2025 at 12:07 PM
If I identified the paper you are mentioning correctly, it was later on criticized here share.google/kvHnQjtXCyIJ...
Reposted
Also from the GitHub repo: antibody antigen docking performance comparison to Boltz-1 and AF-2.3
November 28, 2024 at 2:36 PM
Also from the GitHub repo: antibody antigen docking performance comparison to Boltz-1 and AF-2.3