Systems Biology of Infection Laboratory @ UAB Barcelona
@sysbiouab.bsky.social
Our group is interested in understanding how pathogenic bacteria interact with host cells from a Systems Biology perspective.
Reposted by Systems Biology of Infection Laboratory @ UAB Barcelona
ProtGPS can predict protein location based on sequence and guide the design for novel protein with precise compartmentalisation - new AI tool for protein biology beyond the AlphaFold!! 👏| Science www.science.org/doi/10.1126/...
Protein codes promote selective subcellular compartmentalization
Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...
www.science.org
February 8, 2025 at 10:13 AM
ProtGPS can predict protein location based on sequence and guide the design for novel protein with precise compartmentalisation - new AI tool for protein biology beyond the AlphaFold!! 👏| Science www.science.org/doi/10.1126/...
Reposted by Systems Biology of Infection Laboratory @ UAB Barcelona
PPI prediction accuracy doesn't appear to ever exceed ~0.65 when using embeddings from sequence-only protein language models, regardless of model size or fine-tuning scheme www.biorxiv.org/content/10.1...
January 27, 2025 at 4:56 PM
PPI prediction accuracy doesn't appear to ever exceed ~0.65 when using embeddings from sequence-only protein language models, regardless of model size or fine-tuning scheme www.biorxiv.org/content/10.1...