Xiaojing Gao
@synbiogaolab.bsky.social
If anyone wants to kill a few minutes during their (pre-)Thanksgiving travel: gaolab.blog/2025/11/12/i...
November 13, 2025 at 5:18 AM
If anyone wants to kill a few minutes during their (pre-)Thanksgiving travel: gaolab.blog/2025/11/12/i...
Image credit: DALL-E. Not long ago I wouldn't have imagined my lab making our own nanobodies, the same way that I wouldn't have imagined myself making any image worth posting. Grateful to stand on the shoulders of so many protein designers.
September 24, 2025 at 4:32 PM
Image credit: DALL-E. Not long ago I wouldn't have imagined my lab making our own nanobodies, the same way that I wouldn't have imagined myself making any image worth posting. Grateful to stand on the shoulders of so many protein designers.
t.co/UmbCz8ajMD Spearheaded by Santi, it’s a tremendous team effort with John, Claudia, Haoyu, Talal, and Xiaowei, and a close collaboration between @brianhie.bsky.social’s and my labs. Can’t wait to see what binders everyone will design with it!
September 24, 2025 at 4:32 PM
t.co/UmbCz8ajMD Spearheaded by Santi, it’s a tremendous team effort with John, Claudia, Haoyu, Talal, and Xiaowei, and a close collaboration between @brianhie.bsky.social’s and my labs. Can’t wait to see what binders everyone will design with it!
doi.org/10.1101/2025... Led by
Nat Kolber with key contributions from
Eerik Kaseniit. We also worked with
@tobiaslanz.bsky.social and Bill Robinson from an Epstein–Barr virus angle.
Nat Kolber with key contributions from
Eerik Kaseniit. We also worked with
@tobiaslanz.bsky.social and Bill Robinson from an Epstein–Barr virus angle.
doi.org
September 19, 2025 at 3:21 AM
doi.org/10.1101/2025... Led by
Nat Kolber with key contributions from
Eerik Kaseniit. We also worked with
@tobiaslanz.bsky.social and Bill Robinson from an Epstein–Barr virus angle.
Nat Kolber with key contributions from
Eerik Kaseniit. We also worked with
@tobiaslanz.bsky.social and Bill Robinson from an Epstein–Barr virus angle.
In collaboration with Wing Wong's lab, co-led by Sophia Lu & @Xiaowei0402 (don't miss their respective posters at ICML GenBio Workshop and Protein Engineering GRC), with key contributions from @santimillef & Haoyu Dai.
July 17, 2025 at 5:08 PM
In collaboration with Wing Wong's lab, co-led by Sophia Lu & @Xiaowei0402 (don't miss their respective posters at ICML GenBio Workshop and Protein Engineering GRC), with key contributions from @santimillef & Haoyu Dai.
Thank you, Scott! We certainly hope we could go that far...
April 3, 2025 at 9:17 PM
Thank you, Scott! We certainly hope we could go that far...
More importantly, for diseases that have to be addressed using nucleic acid therapies, such as some recalcitrant cancers, RNA offers the safer option than the more conventional DNA vectors, because RNA is less likely to leave permanent marks in the patients' cells.
April 3, 2025 at 9:05 PM
More importantly, for diseases that have to be addressed using nucleic acid therapies, such as some recalcitrant cancers, RNA offers the safer option than the more conventional DNA vectors, because RNA is less likely to leave permanent marks in the patients' cells.
If I might clumsily point out the economic impact: our project germinated from Impetus Grants @norngroup.bsky.social and an NIH trailblazer grant that add up to ~$0.5M, and now our company supports a dozen employees.
April 3, 2025 at 9:05 PM
If I might clumsily point out the economic impact: our project germinated from Impetus Grants @norngroup.bsky.social and an NIH trailblazer grant that add up to ~$0.5M, and now our company supports a dozen employees.
Thank you, Daryl. Hope all is well!
April 3, 2025 at 8:40 PM
Thank you, Daryl. Hope all is well!
We were inspired by pioneering humanization works from Roybal and @chembiobryan.bsky.social labs. We especially stood on the shoulders of @mokhalil.bsky.social lab's synZiFTRs.
March 1, 2025 at 4:09 AM
We were inspired by pioneering humanization works from Roybal and @chembiobryan.bsky.social labs. We especially stood on the shoulders of @mokhalil.bsky.social lab's synZiFTRs.
As is typical of such works, we built on what came before us, esp. the ZF programming model developed by @hsnajafabadi.bsky.social et al, and the protein language model-guided optimization demonstrated by @brianhie.bsky.social et al and others.
March 1, 2025 at 4:09 AM
As is typical of such works, we built on what came before us, esp. the ZF programming model developed by @hsnajafabadi.bsky.social et al, and the protein language model-guided optimization demonstrated by @brianhie.bsky.social et al and others.